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利用归因分数评估疾病负担的不同方法:以智利的疼痛和慢性肌肉骨骼疾病为例。

Different Alternatives to Assess the Burden of Disease Using Attributable Fraction on a Disability Variable: The Case of Pain and Chronic Musculoskeletal Disorders in Chile.

机构信息

Unidad de Evaluación de Tecnologías Sanitarias, Centro de Invetsigación Clínica, Pontificia Universidad Católica de Chile, Chile; Departamento de Salud Pública, Pontificia Universidad Católica de Chile, Chile; Health Services & Population Research Department, IoPPN, King's College London, England, UK.

Asociación Chilena para el Estudio del Dolor, ACHED, Chile.

出版信息

Value Health Reg Issues. 2021 Dec;26:15-23. doi: 10.1016/j.vhri.2020.12.007. Epub 2021 Mar 22.

Abstract

OBJECTIVES

To estimate the burden of disease through 4 complementary procedures to years lived with disability (YLDs) using the concept of attributable fraction and including analysis of subdomains of disability.

METHODS

We explored the burden on disability for 7 common musculoskeletal disorders (CMD) using the 2009 to 2010 Chilean National Health Survey, which included the Community Oriented Programme for the Control of Rheumatic Disease Core Questionnaire to identify cases with CMD, and an 8-domain questionnaire for health state descriptions. We calculated the proportion of disability attributable to pain in the general population and people with CMD. We also estimated the burden of CMD expressed as YLD and as the proportion of the disability in the general population attributable to people with CMD, with a particular focus in the pain domain of disability. Second order of uncertainty around point estimations was also characterized.

RESULTS

Pain domain of disability accounted for 23.4% of the total disability in the general population, and between 20% (fibromyalgia) to 27.1% (osteoarthritis of the hip) in people with some of the selected CMD. People with chronic musculoskeletal pain accounted for 21.2% of total disability from general population, which generated 1.2 million of YLD (6679 YLD/100 000 inhabitants). Chronic low back pain and osteoarthritis of the knee were in the top position of specific CMDs, explaining the highest national burden.

CONCLUSION

Pain is an essential component of disability in people with CMD and also in the general population. The approach used can be easily applied to other health conditions and other domains of disability.

摘要

目的

通过使用归因分数的概念并包括对残疾亚领域的分析,通过 4 种补充残疾年限 (YLD) 的程序来估计疾病负担。

方法

我们使用 2009 年至 2010 年智利国家健康调查,该调查包括面向社区的控制风湿疾病核心问卷来识别患有 CMD 的病例,以及 8 个领域的健康状况描述问卷,探索了 7 种常见肌肉骨骼疾病 (CMD) 的残疾负担。我们计算了普通人群和患有 CMD 的人群中归因于疼痛的残疾比例。我们还根据 YLD 来衡量 CMD 的负担,以及归因于患有 CMD 的人群的残疾在普通人群中的比例,特别关注残疾的疼痛领域。还对点估计的二阶不确定度进行了特征描述。

结果

残疾的疼痛领域占普通人群总残疾的 23.4%,在某些选定的 CMD 人群中,残疾的疼痛领域占 20%(纤维肌痛)到 27.1%(髋关节骨关节炎)。患有慢性肌肉骨骼疼痛的人群占普通人群总残疾的 21.2%,这导致了 120 万残疾年(6679 残疾年/每 10 万人)。慢性下背痛和膝关节骨关节炎在特定 CMD 中处于最高位置,解释了最高的国家负担。

结论

疼痛是患有 CMD 的人群和普通人群残疾的一个重要组成部分。所使用的方法可以很容易地应用于其他健康状况和其他残疾领域。

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