Albassam Ahmed A, Alanazi Arwa, Alhaqbani Norah, Alhoti Fatima, Almalki Ziyad S, Alshehri Ahmed M, Alzahrani Jamaan
Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Complement Ther Clin Pract. 2021 May;43:101324. doi: 10.1016/j.ctcp.2021.101324. Epub 2021 Feb 2.
This study aimed to estimate the prevalence of the potential drug-herbal interaction among patients with chronic diseases in Al-Kharj, Saudi Arabia and to explore factors associated with the potential of drug-herbal interaction.
A cross-sectional study was conducted through interview-based questionnaire at outpatient clinics in Al-Kharj. The study included patients with chronic diseases who used herbal products.
This study included 336 patients in total. The mean age of participants was 52.4 ± 12.0 years, and their most-used medications were metformin, atorvastatin, and aspirin, while their most-used herbs were ginger (74.7%), mint (72%), and cumin (66.7%). In 310 out of 336 (92.26%) cases, at least one potential drug-herbal interaction was found, and most of these interactions (84%) were moderate.
A substantial percentage of potential drug-herbal interactions were found among patients with chronic diseases. Healthcare providers are encouraged to discuss the safety and efficacy of herbal products with their patients.
本研究旨在估计沙特阿拉伯哈吉尔地区慢性病患者中潜在药物 - 草药相互作用的患病率，并探索与药物 - 草药相互作用可能性相关的因素。
通过在哈吉尔门诊基于访谈的问卷进行横断面研究。该研究纳入了使用草药产品的慢性病患者。
本研究共纳入336名患者。参与者的平均年龄为52.4±12.0岁，他们最常使用的药物是二甲双胍、阿托伐他汀和阿司匹林，而他们最常使用的草药是生姜（74.7%）、薄荷（72%）和孜然（66.7%）。在336例中的310例（92.26%）中，发现至少一种潜在的药物 - 草药相互作用，并且这些相互作用中的大多数（84%）为中度。
在慢性病患者中发现了相当比例的潜在药物 - 草药相互作用。鼓励医疗保健提供者与患者讨论草药产品的安全性和有效性。
