沙特阿拉伯慢性病患者中药物与草药相互作用的可能性。
The potential of drug-herbal interaction among patients with chronic diseases in Saudi Arabia.
作者信息
Albassam Ahmed A, Alanazi Arwa, Alhaqbani Norah, Alhoti Fatima, Almalki Ziyad S, Alshehri Ahmed M, Alzahrani Jamaan
机构信息
Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
出版信息
Complement Ther Clin Pract. 2021 May;43:101324. doi: 10.1016/j.ctcp.2021.101324. Epub 2021 Feb 2.
AIMS
This study aimed to estimate the prevalence of the potential drug-herbal interaction among patients with chronic diseases in Al-Kharj, Saudi Arabia and to explore factors associated with the potential of drug-herbal interaction.
METHOD
A cross-sectional study was conducted through interview-based questionnaire at outpatient clinics in Al-Kharj. The study included patients with chronic diseases who used herbal products.
RESULTS
This study included 336 patients in total. The mean age of participants was 52.4 ± 12.0 years, and their most-used medications were metformin, atorvastatin, and aspirin, while their most-used herbs were ginger (74.7%), mint (72%), and cumin (66.7%). In 310 out of 336 (92.26%) cases, at least one potential drug-herbal interaction was found, and most of these interactions (84%) were moderate.
CONCLUSION
A substantial percentage of potential drug-herbal interactions were found among patients with chronic diseases. Healthcare providers are encouraged to discuss the safety and efficacy of herbal products with their patients.
目的
本研究旨在估计沙特阿拉伯哈吉尔地区慢性病患者中潜在药物 - 草药相互作用的患病率，并探索与药物 - 草药相互作用可能性相关的因素。
方法
通过在哈吉尔门诊基于访谈的问卷进行横断面研究。该研究纳入了使用草药产品的慢性病患者。
结果
本研究共纳入336名患者。参与者的平均年龄为52.4±12.0岁，他们最常使用的药物是二甲双胍、阿托伐他汀和阿司匹林，而他们最常使用的草药是生姜（74.7%）、薄荷（72%）和孜然（66.7%）。在336例中的310例（92.26%）中，发现至少一种潜在的药物 - 草药相互作用，并且这些相互作用中的大多数（84%）为中度。
结论
在慢性病患者中发现了相当比例的潜在药物 - 草药相互作用。鼓励医疗保健提供者与患者讨论草药产品的安全性和有效性。
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