Park clinic, 4, Gorky Terrace, Minto Park, Kolkata, 700017, India.
Eur Spine J. 2021 Oct;30(10):2852-2856. doi: 10.1007/s00586-021-06819-y. Epub 2021 Mar 26.
Management of vertebral and discovertebral lesions depends on highly specific modalities like biopsy and histopathology. The transpedicular and transforaminal routes have gained popularity for obtaining samples for diagnosing these lesions. Sample inadequacy plays an important part in lowering the diagnostic accuracy. Present study introduces a technical modification by using a kyphoplasty cannula and pituitary forceps through it thus improving sample adequacy and diagnostic accuracy.
Seventy-one patients with radiological evidence of spinal lesions from T1 to S1 were included. After obtaining samples via the transpedicular route they were sent for aerobic, anaerobic, acid fast bacilli & fungal cultures, Mycobacterium Tuberculosis/Radio Immuno Frequency (MTB/RIF) Assay and histopathological examination. In lesions with minimal vertebral erosions the transforaminal route was used to obtain samples from the disc space.
Sixty-eight patients (95.8%) had a definite diagnosis of which 37 patients (54.4%) tested positive for vertebral osteomyelitis/discitis. All the samples were found to be adequate on histopathological examination. The remaining 3 patients showed chronic inflammation and responded to oral and intravenous antibiotics. None of the patients underwent repeat biopsy. There were no perioperative complications.
Percutaneous transpedicular biopsy has evolved as the intervention of choice in diagnosing radiologically proven vertebral body lesions. Our technique of using a pituitary forceps through a cannula is highly effective in getting an adequate representative sample with excellent accuracy in diagnosis. This procedure is beneficial for soft tissue lesions and for infective pathology especially discitis.
对椎体和椎骨病变的处理取决于活检和组织病理学等高度特定的方式。经皮穿刺椎弓根和椎间孔入路因其可获取用于诊断这些病变的样本而受到欢迎。样本不足是降低诊断准确性的重要因素。本研究通过使用经皮穿刺椎弓根入路的球囊扩张套管和垂体咬骨钳来获取样本,从而提高了样本的充足性和诊断的准确性。
纳入了 T1 至 S1 段有影像学证据的 71 例脊柱病变患者。通过经皮穿刺椎弓根入路获取样本后,将其送往进行需氧、厌氧、抗酸杆菌和真菌培养、结核分枝杆菌/放射性免疫频率(MTB/RIF)检测和组织病理学检查。在椎体侵蚀最小的病变中,使用经椎间孔入路从椎间盘空间获取样本。
68 例患者(95.8%)有明确的诊断,其中 37 例(54.4%)被检测出患有椎体骨髓炎/椎间盘炎。所有样本在组织病理学检查中均被认为是充足的。其余 3 例患者表现为慢性炎症,对口服和静脉用抗生素有反应。没有患者需要再次进行活检。没有围手术期并发症。
经皮穿刺椎弓根活检已成为诊断影像学证实的椎体病变的首选干预手段。我们使用套管内垂体咬骨钳的技术在获取充足且具有出色诊断准确性的代表性样本方面非常有效。该程序对软组织病变和感染性病变(特别是椎间盘炎)有益。