Serao Armando, Ambrosini Francesca, Cavallone Barbara, Borra Tiziana, Di Stasio Andrea
Department of Urology, Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
Department of Urology, Policlinico San Martino Hospital, University of Genoa, Italy.
Urologia. 2022 Nov;89(4):641-644. doi: 10.1177/03915603211001181. Epub 2021 Mar 29.
Well-differentiated papillary mesothelioma (WDPM) is a very rare neoplasm. Most of WDPM are asymptomatic and are often incidentally detected during surgery. This report describes a case of WDPM of the peritoneum unexpectedly diagnosed in a male with a spontaneous intraperitoneal bladder rupture.
A 65-year-old male presented to our Emergency Department in November 2019 with a two-day history of anuria, abdominal pain, distention, and sepsis. The CT scan reported a large amount of extra and intraperitoneal free fluid. The CT cystogram showed bladder perforations on the dome and on the left lateral wall which was repaired through exploratory laparotomy. Intraoperatively, we encountered extensive suppurative peritonitis with large fibrino-purulent exudation. The purulent perivesical peritoneum was dissected and sent for histopathological examination which unexpectedly resulted in WDPM of the peritoneum.
Although we can't affirm with certainty, this case would seem to suggest that WDPM had played a role in patient's clinical presentation. However, further research is necessary to draw stronger conclusion.
高分化乳头状间皮瘤(WDPM)是一种非常罕见的肿瘤。大多数WDPM无症状,常在手术中偶然发现。本报告描述了一例在一名自发性腹膜内膀胱破裂男性患者中意外诊断出的腹膜WDPM病例。
一名65岁男性于2019年11月因无尿、腹痛、腹胀和脓毒症两天就诊于我院急诊科。CT扫描显示腹腔内和腹膜外有大量游离液体。CT膀胱造影显示膀胱顶部和左侧壁穿孔,通过剖腹探查术进行了修复。术中,我们遇到广泛的化脓性腹膜炎,伴有大量纤维蛋白脓性渗出物。切除了化脓性膀胱周围腹膜并送去进行组织病理学检查,结果意外发现为腹膜WDPM。
虽然我们不能肯定,但该病例似乎表明WDPM在患者的临床表现中起了作用。然而,需要进一步研究以得出更有力的结论。