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染发所致浅表性剥脱性食管炎(EDS):病例报告及文献综述

Esophagitis Dissecans Superficialis (EDS) Secondary to Hair Dye Ingestion: Case Report and Literature Review.

作者信息

Then Eric Omar, Grantham Tyler, Lopez Michell, Reddy Madhavi, Gaduputi Vinaya

机构信息

Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Clinical Affiliate of The Mount Sinai Hospital, Brooklyn, NY 11201, USA.

Division of Gastroenterology and Hepatology, SBH Health System, Bronx, NY 10457, USA.

出版信息

Clin Pract. 2021 Mar 29;11(2):185-189. doi: 10.3390/clinpract11020026.

DOI:10.3390/clinpract11020026
PMID:33805260
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8103253/
Abstract

Esophagitis dissecans superficialis (EDS) is a rare and underdiagnosed esophageal lesion characterized by sloughing of the esophageal mucosa that has been associated with medications, various autoimmune disorders, and exposure to some chemical irritants. Anatomically, EDS is most commonly seen in the middle and distal thirds of the esophagus. When present, EDS is best treated by discontinuing the offending agent and initiating pharmacologic therapy with proton pump inhibitors. Steroids may also be effective if the etiology is autoimmune in nature. Our case highlights a 65-year-old female diagnosed with EDS after incidental ingestion of hair dye containing resorcinol and para-phenylenediamine (PPD).

摘要

浅表性剥脱性食管炎(EDS)是一种罕见且易被漏诊的食管病变,其特征为食管黏膜脱落,与药物、多种自身免疫性疾病以及接触某些化学刺激物有关。从解剖学角度看,EDS最常见于食管的中下段。一旦出现EDS,最佳治疗方法是停用致病因素,并开始使用质子泵抑制剂进行药物治疗。如果病因是自身免疫性的,类固醇药物可能也有效。我们的病例突出显示了一名65岁女性,在偶然摄入含有间苯二酚和对苯二胺(PPD)的染发剂后被诊断为EDS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cba/8103253/2413f1080609/clinpract-11-00026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cba/8103253/2413f1080609/clinpract-11-00026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cba/8103253/2413f1080609/clinpract-11-00026-g001.jpg

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本文引用的文献

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Case Rep Gastroenterol. 2020 Apr 17;14(1):172-177. doi: 10.1159/000506935. eCollection 2020 Jan-Apr.
2
IL-24 contributes to skin inflammation in Para-Phenylenediamine-induced contact hypersensitivity.白细胞介素-24 有助于对苯二胺诱导的接触性超敏反应中的皮肤炎症。
Sci Rep. 2019 Feb 12;9(1):1852. doi: 10.1038/s41598-018-38156-4.
3
Esophagitis dissecans superficialis due to severe nonsteroidal anti-inflammatory drugs toxicity.
严重非甾体抗炎药毒性所致的浅表性剥脱性食管炎
Presse Med. 2018 Jul-Aug;47(7-8 Pt 1):695-697. doi: 10.1016/j.lpm.2018.05.004. Epub 2018 Jun 12.
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Hair Dye poisoning: "An early intervention".染发剂中毒:“早期干预”
Pak J Med Sci. 2018 Jan-Feb;34(1):230-232. doi: 10.12669/pjms.341.14123.
5
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Para-phenylenediamine allergy: current perspectives on diagnosis and management.对苯二胺过敏:诊断与管理的当前观点
J Asthma Allergy. 2017 Jan 18;10:9-15. doi: 10.2147/JAA.S90265. eCollection 2017.
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