一名患有胎儿苯妥英综合征患者的甲病

Onychopathy in a patient with fetal hydantoin syndrome.

作者信息

Verdeguer J M, Ramon D, Moragon M, Betlloch I, Jorda E, Planelles M V

机构信息

Department of Dermatology, Universitary Hospital Clinic, Valencia, Spain.

出版信息

Pediatr Dermatol. 1988 Feb;5(1):56-7. doi: 10.1111/j.1525-1470.1988.tb00885.x.

DOI:10.1111/j.1525-1470.1988.tb00885.x

PMID:3380763

Abstract

Hydantoin is an anticonvulsant drug with several side effects. A teratogenic potential has been suggested. The fetal hydantoin syndrome is an entity that consists of a broad range of morphologic and developmental disorders in children born of epileptic mothers exposed to hydantoin during pregnancy. We treated a girl in whom onychopathy was a monosymptomatic or mild form of this syndrome.

摘要

乙内酰脲是一种具有多种副作用的抗惊厥药物。有人提出它有致畸潜力。胎儿乙内酰脲综合征是指在孕期接触乙内酰脲的癫痫母亲所生儿童中出现的一系列广泛的形态学和发育障碍。我们治疗了一名女孩，她的甲病是该综合征的单一症状或轻度形式。