Biswas Gautam, Panchal Karnav Bharat, Jain Prateek V, Manikantan Kapila, Sharan Rajeev, Arun Pattatheyil
Department of Plastic and Reconstructive Surgery, TATA Medical Center, Kolkata, West Bengal, India.
Department of Head and Neck Surgery, TATA Medical Center, Kolkata, West Bengal, India.
Indian J Plast Surg. 2021 Jan;54(1):53-57. doi: 10.1055/s-0040-1721522. Epub 2020 Nov 30.
The process of reconstruction of tracheal defects is complex and still not optimum. Options range from using staged reconstructions, combining flaps with autologous or alloplastic implants, as well as use of tissue-engineered constructs combined with vascularized tissues which are lined with cell cultures. Staged reconstructions using prelaminated epithelium, and prefabricated flaps, help in reconstruction of this complex structure. Prefabricating the flap at a different site allows for integration of the tissues prior to its transfer. This article reports two patients planned for tracheal reconstruction for the purpose of advanced papillary carcinoma of the thyroid invading the trachea. Staged reconstruction using a prefabricated radial artery forearm flap (RAFF) and split rib cartilage was performed. In the second patient, a young girl, a similar construct of the RAFF, prelaminated with buccal mucosa, was performed. However, in the latter case, an intraoperative decision by the head and neck team to limit excision of the trachea sparing the mucosa was taken; the reconstruct in the forearm was redundant and needed to be discarded, replacing the defect with a free superficial circumflex iliac artery perforator (SCIP) flap. At 3 years follow-up, both the patients are free of disease, with the construct serving its purpose in the older female.
气管缺损的重建过程复杂且仍未达到最佳状态。方法包括采用分期重建、将皮瓣与自体或异体植入物相结合,以及使用组织工程构建体与内衬细胞培养物的血管化组织相结合。使用预分层上皮和预制皮瓣的分期重建有助于重建这种复杂结构。在不同部位预制皮瓣可使组织在转移前实现整合。 本文报告了两名计划进行气管重建的患者,目的是治疗侵犯气管的晚期甲状腺乳头状癌。采用预制桡动脉前臂皮瓣(RAFF)和劈开肋软骨进行分期重建。在第二名患者中,是一名年轻女孩,采用了类似的预分层颊黏膜的RAFF构建体。然而,在后一例中,头颈团队在术中决定限制气管切除,保留黏膜;前臂的重建物多余,需要舍弃,改用游离旋髂浅动脉穿支(SCIP)皮瓣修复缺损。 在3年的随访中,两名患者均无疾病,该构建体在老年女性患者中发挥了作用。