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[Total synthesis and properties of prostaglandins. XIV. Amide derivatives of 3alpha-tetrahydrofuranyloxy-5-hydroxyimino-2beta- (3alpha-tetrahydrofuranyloxy-trans-1-octenyl)-cyclopentane- 1alpha-acetic acid].

作者信息

Kudriashova V V, Dikovskaia K I, Kalnin'sh A P, Kropivets L S, Freĭmanis Ia F

出版信息

Bioorg Khim. 1988 Feb;14(2):216-21.

PMID:3382435
Abstract

Several novel prostaglandins containing an amide group in the alpha-chain have been prepared by the mixed carbonic anhydride method from 3 alpha-tetrahydrofuranyloxy-5-hydroxyimino-2 beta-(3 alpha- tetrahydrofuranyloxy-trans-1-octenyl)-cyclopentane-1 alpha-acetic acid and omega-amino acids with a linear chain of varying length (CH2-group number from 1 to 7). The physico-chemical properties of the title compounds were studied.

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