Department of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.
Department of Orthopaedic Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.
PLoS One. 2021 Apr 8;16(4):e0249819. doi: 10.1371/journal.pone.0249819. eCollection 2021.
Hip fracture incidence is increasing with rapid aging of the population and regular physical activity (RPA) is an important modifiable protective factor for fracture. However, the association between the risk of hip fractures and changes in RPA status in the general population remains unknown. Thus, we explore the association between the risk of hip fracture and changes in RPA status.
We studied 4,984,144 individuals without fractures within a year whose data were registered in the Korean National Health Insurance Service database. Baseline physical activity level was assessed using a standardized self-reported questionnaire during two consecutive national health screening surveys performed in Korea from 2009 to 2012. The risk of hip fracture between 2013 and 2016 according to change in RPA was prospectively analyzed. Participants were divided into those who were always inactive, became inactive, became active, and were always active.
Compared to participants who were always inactive, those who became inactive exhibited a 0.12/1,000 person-years (PY) reduction in hip fracture incidence rate (IR) [aHR: 0.865; 95% confidence interval (CI): 0.824-0.908]. Participants who became active, and those who were always active, exhibited a 0.24/1,000 PY reduction in IR (aHR: 0.827; 95% CI: 0.787-0.870) and a 0.39/1,000 PY reduction in IR (aHR: 0.691; 95% CI: 0.646-0.740), respectively.
Changes in RPA status were associated with the risk of hip fracture; consistent RPA was related to the maximum benefit for risk reduction in the general population.
随着人口老龄化的快速发展，髋部骨折的发病率正在上升，而有规律的体育活动（RPA）是骨折的一个重要可改变的保护因素。然而，普通人群中髋部骨折风险与 RPA 状态变化之间的关系尚不清楚。因此，我们探讨了髋部骨折风险与 RPA 状态变化之间的关系。
我们研究了 4984144 名在一年内无骨折的个体，其数据登记在韩国国家健康保险服务数据库中。在韩国于 2009 年至 2012 年进行的两次连续国家健康筛查调查中，使用标准化的自我报告问卷评估了基线体力活动水平。前瞻性分析了 2013 年至 2016 年期间 RPA 变化与髋部骨折风险之间的关系。参与者被分为始终不活跃、变得不活跃、变得活跃和始终活跃。
与始终不活跃的参与者相比，变得不活跃的参与者髋部骨折发生率（IR）降低了 0.12/1000 人年（aHR：0.865；95%置信区间[CI]：0.824-0.908）。变得活跃和始终活跃的参与者的 IR 分别降低了 0.24/1000 人年（aHR：0.827；95%CI：0.787-0.870）和 0.39/1000 人年（aHR：0.691；95%CI：0.646-0.740）。
RPA 状态的变化与髋部骨折风险相关；在普通人群中，始终保持 RPA 与最大程度降低风险有关。
