Department of Cell and Developmental Biology, University College London, London, United Kingdom.
Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Handb Clin Neurol. 2021;178:115-129. doi: 10.1016/B978-0-12-821377-3.00004-0.
We begin with the functions of the striate cortex (area V1 of the visual cortex) and end with a review of the effects of damage to striate cortex or its inputs; namely, homonymous hemifield defects. Clinical and anatomical studies accrued over the past 25 years have modified our understanding of the role of V1 in vision. We discuss the evidence that V1 is not the sole recipient of visual signals; is not the earliest recipient of visual signals; and is not essential for conscious vision. In the second section, we give a brief history of how the visual field was found to be represented in striate cortex, then cover the work that has demonstrated the overrepresentation of the central region of vision in humans. The common patterns of visual field disturbance caused by damage to the retrochiasmal visual system are discussed, with some less common examples shown as brief case studies.
我们首先介绍纹状皮层(视觉皮层 V1 区)的功能,最后回顾纹状皮层或其输入(即同侧偏盲)受损的影响。过去 25 年来的临床和解剖研究改变了我们对 V1 在视觉中的作用的理解。我们讨论了 V1 并非是视觉信号的唯一接收者、并非是视觉信号的最早接收者、以及对于意识视觉并非是必需的证据。在第二部分中,我们简要回顾了如何发现纹状皮层中存在视野的代表,然后介绍了证明人类视觉中央区域过表达的工作。讨论了由视交叉后视觉系统损伤引起的常见视野障碍模式,并展示了一些不太常见的简要案例研究。