Approximate back-projection method for improving lateral resolution in circular-scanning-based photoacoustic tomography.

PURPOSE

In circular-scanning-based photoacoustic tomography (PAT), the effect of finite transducer aperture has not been effectively resolved. The goal of this paper is to propose a practical reconstruction method that accounts for the finite transducer aperture to improve the lateral resolution.

METHODS

We for the first time propose to calculate the spatial-temporal response (STR) of the employed finite-sized transducer in a forward model, and then compensate the time delay and the directional sensitivity of the transducer in the framework of the back-projection method. Both simulation and phantom experiments were carried out to evaluate the lateral resolution improvement with the proposed method. The performance of this new method for imaging complicated targets was also assessed by calculating the mean image gradient.

RESULTS

Simulation results showed that with this new method the lateral resolution for off-center targets can be as good as that for the center targets. Phantom experimental results showed that this new method can improve the lateral resolution more than two times for a point target about 5 mm far from the rotation center. Phantom experimental results also showed that many blurred fine structures of a piece of leaf veins at the off-center regions were well restored with the new method, and the mean image gradient improved about 1.3 times.

CONCLUSION

The proposed new method can effectively account for the effect of finite transducer aperture for circular-scanning-based PAT in homogenous acoustic media. This new method also features its robustness and computational efficiency, so that it is a worthy replacement to the conventional back-projection algorithm in circular-scanning-based PAT. This new method can be of great importance to the design of circular-scanning or spherical-scanning-based PAT systems.