Saldana-Ruiz Nallely, Dominguez Josefina, Ham Sung Wan, Rowe Vincent L, Magee Gregory A, Weaver Fred A, Han Sukgu M, Ziegler Kenneth R
Division of Vascular Surgery, Department of Surgery, University of Southern California, Los Angeles, Calif.
Division of Vascular Surgery, Department of Surgery, University of Southern California, Los Angeles, Calif.
J Vasc Surg. 2021 Oct;74(4):1242-1250. doi: 10.1016/j.jvs.2021.03.023. Epub 2021 Apr 15.
We investigated the association of tunneling technique on patency and amputation in patients undergoing lower extremity bypass for limb ischemia.
The National Vascular Quality Initiative database infrainguinal bypass module from 2008 to 2017 was queried for analysis. We excluded cases with non-great saphenous vein grafts, grafts using multiple segments, aneurysmal disease indications, bypass locations outside the femoral to below the knee popliteal artery or tibial arteries, and missing data on tunneling type and limb ischemia. The main exposure variable was the tunneling type, subcutaneously vs subfascially. Our primary outcomes were primary patency and amputation. The secondary outcomes included primary-assisted patency and secondary patency. Univariate and multivariate logistic regression models were used.
A total of 5497 bypass patients (2835 subcutaneous and 2662 subfascial) were included. Age, race, graft orientation (reversed vs not reversed), bypass donor and recipient vessels, harvest type, end-stage renal disease, smoking, coronary artery bypass graft, congestive heart failure, P2Y12 inhibitor at discharge, surgical site infection at discharge, and indication (rest pain vs tissue loss vs acute ischemia) were analyzed for an association with the tunneling technique (P < .05). Multivariate analyses demonstrated that the tunneling type was not associated with primary patency, primary-assisted patency, secondary patency, or major amputation (P > .05).
Compared with subfascial tunneling, the superficial tunneling technique was not associated with primary patency or major amputation in limb ischemia patients undergoing infrainguinal bypass with a single-segment great saphenous vein.
我们研究了隧道技术与下肢缺血行下肢旁路移植术患者通畅率和截肢情况之间的关联。
查询2008年至2017年国家血管质量倡议数据库的股腘以下旁路移植模块进行分析。我们排除了非大隐静脉移植物、使用多节段移植物、动脉瘤疾病指征、股动脉至膝下腘动脉或胫动脉以外的旁路位置以及隧道类型和肢体缺血数据缺失的病例。主要暴露变量是隧道类型,即皮下隧道与筋膜下隧道。我们的主要结局是原发性通畅率和截肢情况。次要结局包括原发性辅助通畅率和继发性通畅率。使用单因素和多因素逻辑回归模型。
共纳入5497例旁路移植患者(2835例皮下隧道和2662例筋膜下隧道)。分析了年龄、种族、移植物方向(逆转与未逆转)、旁路移植的供体和受体血管、采集类型、终末期肾病、吸烟、冠状动脉旁路移植术、充血性心力衰竭、出院时的P2Y12抑制剂、出院时的手术部位感染以及指征(静息痛与组织缺失与急性缺血)与隧道技术的相关性(P < 0.05)。多因素分析表明,隧道类型与原发性通畅率、原发性辅助通畅率、继发性通畅率或大截肢无关(P > 0.05)。
与筋膜下隧道相比,在使用单节段大隐静脉进行股腘以下旁路移植的肢体缺血患者中,浅表隧道技术与原发性通畅率或大截肢无关。