氧气对使用4-二甲基氨基酚进行的人体和犬类血液中高铁血红蛋白生成的体外研究的影响。
The effect of oxygen on in vitro studies on methemoglobin production in man and dog blood using 4-dimethylaminophenol.
作者信息
Woodman A C, Bright J E, Marrs T C
机构信息
Medical Division Chemical Defence Establishment, Salisbury, Wiltshire, UK.
出版信息
Hemoglobin. 1988;12(1):53-60. doi: 10.3109/03630268808996882.
PMID:3384698
Abstract
Methemoglobin production induced by the addition of 4-dimethylaminophenol to human or beagle blood in vitro is inhibited at high oxyhemoglobin levels. The effect is similar in the two species and probably results from conformational change in hemoglobin consequent on oxygen binding.
摘要
在体外向人或比格犬血液中添加4-二甲基氨基酚所诱导的高铁血红蛋白生成，在高氧合血红蛋白水平时受到抑制。两种物种的这种效应相似，可能是由于氧结合后血红蛋白的构象变化所致。
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