多重用药与抗胆碱能负担量表之间关系的评估。
The evaluation of relationship between polypharmacy and anticholinergic burden scales.
作者信息
Okudur Saadet Koc, Dokuzlar Ozge, Aydin Ali Ekrem, Kocyigit Suleyman Emre, Soysal Pinar, Isik Ahmet Turan
机构信息
Department of Geriatric Medicine, Manisa State Hospital, Manisa, Turkey.
Department of Geriatric Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
出版信息
North Clin Istanb. 2021 Mar 11;8(2):139-144. doi: 10.14744/nci.2020.17136. eCollection 2021.
OBJECTIVE
Polypharmacy and anticholinergic burden are the indicators for the evaluation of the quality of pharmacotherapy in older adults. The aim of this study was to consider which anticholinergic burden scales are more related with polypharmacy among older patients.
METHODS
Four hundred and twenty older adults were evaluated retrospectively in this cross-sectional study. The patient's demographic data, comorbidities, the drugs, and number of drugs were recorded. Anticholinergic burden scales were calculated by a tool named anticholinergic burden calculator.
RESULTS
The participants' mean age was 73.08±8.71. The prevalence of polypharmacy was 32.14%. The highest relationship with polypharmacy was observed for drug burden index (DBI) (odds ratio 10.87, p<0.001).
CONCLUSION
Our study demonstrated that polypharmacy and DBI scores were more related than other anticholinergic burden scales in older adults.
目的
多重用药和抗胆碱能负担是评估老年人药物治疗质量的指标。本研究的目的是探讨在老年患者中，哪些抗胆碱能负担量表与多重用药的相关性更强。
方法
在这项横断面研究中，对420名老年人进行了回顾性评估。记录了患者的人口统计学数据、合并症、所用药物及药物数量。使用一种名为抗胆碱能负担计算器的工具计算抗胆碱能负担量表。
结果
参与者的平均年龄为73.08±8.71岁。多重用药的患病率为32.14%。药物负担指数（DBI）与多重用药的相关性最高（优势比10.87，p<0.001）。
结论
我们的研究表明，在老年人中，多重用药与DBI评分的相关性比其他抗胆碱能负担量表更强。
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