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使用基于胶原蛋白的止血贴片加强直肠吻合术:病例系列报告

Reinforcement of rectal anastomoses with a collagen-based haemostatic patch: a case series report.

作者信息

Kornfeld Dan

机构信息

Capio Sankt Görans Hospital, Stockholm, Sweden.

出版信息

J Surg Case Rep. 2021 Apr 13;2021(4):rjaa228. doi: 10.1093/jscr/rjaa228. eCollection 2021 Apr.

Abstract

In this case series report of 10 colorectal cancer patients, a polyethylene glycol-coated collagen-based haemostatic patch was applied after rectal resection to reinforce rectal anastomoses and reduce anastomotic leakage. Patients underwent rectal resection and anastomoses were stapled in place. The patch-Hemopatch®-was applied to 75% of the anastomotic circumference. The surgeon judged the simplicity of application using a reinforcement of rectal anastomosis score. Mean age of patients was 68.1 (range 50-94) years. The patch was successfully applied in eight patients; in seven patients, patch application was straightforward or only slightly complex, according to the reinforcement of rectal anastomosis score. Seven of eight patients experienced no leakage or signs of stricture 6 weeks post-surgery. All patients underwent radical resection. It is possible to apply Hemopatch® during colorectal surgery. However, the patch application procedure needs to be standardized and efficacy needs to be evaluated by conducting larger clinical studies.

摘要

在这份关于10例结直肠癌患者的病例系列报告中,在直肠切除术后应用了一种聚乙二醇涂层的胶原蛋白基止血贴片,以加强直肠吻合并减少吻合口漏。患者接受直肠切除术,吻合口用吻合器固定。将Hemopatch®贴片应用于吻合口周长的75%。外科医生使用直肠吻合加强评分来判断应用的简易程度。患者的平均年龄为68.1岁(范围50 - 94岁)。该贴片在8例患者中成功应用;根据直肠吻合加强评分,7例患者的贴片应用操作简单或仅稍有复杂。8例患者中有7例在术后6周无漏液或狭窄迹象。所有患者均接受了根治性切除。在结直肠手术期间应用Hemopatch®是可行的。然而,贴片应用程序需要标准化,并且需要通过开展更大规模的临床研究来评估其疗效。

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