Department of Surgery, Division of Trauma and Surgical Critical Care, 14506Kendall Regional Medical Center, Miami, FL, USA.
Department of Surgery, University of South Florida, Tampa, FL, USA.
Am Surg. 2022 Nov;88(11):2670-2677. doi: 10.1177/00031348211011112. Epub 2021 Apr 18.
Extracorporeal membrane oxygenation (ECMO) has become an increasingly used treatment modality for severe respiratory insufficiency in trauma patients. Examining ECMO use specifically in blunt and penetrating traumas can aid in directing future protocols. We aim to evaluate the outcomes of ECMO use in both blunt and penetrating trauma patients through a systematic review of current literature.
An online search of 2 databases (PubMed and Google Scholar) was performed to analyze studies, which evaluated the use of ECMO in blunt and penetrating traumas. Preferred Reporting Items for Systematic Reviews and Meta-Analysis and Grading of Recommendations Assessment, Development and Evaluation guidelines were followed. Data extracted included mechanism of injury, injury severity scores (ISSs), complications, and mortality rates.
The search demonstrated 9 studies that met our review inclusion criteria. A total of 207 patients were included, of which 64 (30.9%) were non-survivors and 143 (69.1%) were survivors. There was a total of 201 blunt traumas with 61 (30.3%) deaths, whereas penetrating traumas had 2 deaths (33.3%) out of 6 total patients. Complications reported included acute renal failure, hemorrhage at the cannula site, and transient neurological deficits. Most studies found better survival rates and less complications in younger patients and those with lower ISS.
Expanding the use of ECMO to include blunt and penetrating trauma patients provides the trauma surgeons with another crucial potentially lifesaving tool with an overall survival rate of 70%. Anticipating increased future use of ECMO in blunt and penetrating trauma patients, distinct protocols ought to be instilled to better address the care needed for these critically ill trauma patients.
体外膜肺氧合(ECMO)已成为治疗创伤患者严重呼吸功能不全的一种越来越常用的治疗方法。专门研究创伤患者中 ECMO 的使用情况有助于指导未来的方案。我们旨在通过对现有文献的系统回顾来评估 ECMO 在钝性和穿透性创伤患者中的使用效果。
在 2 个数据库(PubMed 和 Google Scholar)上进行在线搜索,以分析评估 ECMO 在钝性和穿透性创伤中使用的研究。遵循系统评价和荟萃分析的首选报告项目以及推荐评估、制定和评估指南。提取的数据包括损伤机制、损伤严重程度评分(ISS)、并发症和死亡率。
搜索结果显示有 9 项符合我们的审查纳入标准的研究。共有 207 名患者被纳入研究,其中 64 名(30.9%)是非幸存者,143 名(69.1%)是幸存者。共有 201 例钝性创伤,61 例(30.3%)死亡,而 6 例穿透性创伤患者中,有 2 例(33.3%)死亡。报告的并发症包括急性肾功能衰竭、插管部位出血和短暂性神经功能缺损。大多数研究发现,年轻患者和 ISS 较低的患者的生存率更高,并发症更少。
将 ECMO 的应用扩展到包括钝性和穿透性创伤患者,为创伤外科医生提供了另一种至关重要的潜在救生工具,总体生存率为 70%。预计未来在钝性和穿透性创伤患者中会增加 ECMO 的使用,因此应该制定明确的方案,以更好地满足这些重症创伤患者的护理需求。