Takagawa Shu, Kobayashi Naomi, Yukizawa Yohei, Oishi Takayuki, Tsuji Masaki, Misumi Toshihiro, Inaba Yutaka
Department of Orthopaedic Surgery, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan.
Department of Biostatistics, Yokohama City University School of Medicine, 3-9, Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
BMC Musculoskelet Disord. 2021 Apr 20;22(1):368. doi: 10.1186/s12891-021-04211-x.
Rehabilitation is an effective procedure for promoting functional recovery after simultaneous bilateral total knee arthroplasty (TKA); however, it has been cited as a significant economic burden of medical care. We hypothesized that preoperative factors, including age, sex, body mass index, living alone, the knee society function score (KSS), the American society of anesthesiologists (ASA) class, hemoglobin (Hb), albumin level, mean range of motion, and the Kellgren-Lawrence grade, would predict prolonged rehabilitation utilization.
In total, 191 patients undergoing simultaneous bilateral TKA in a single hospital were enrolled. The successful compliance group included patients who completed their rehabilitation program and could return to their residence within 3 weeks after surgery (n = 132), whereas the delayed group included the remaining patients (n = 59). Logistic regression analysis was performed using preoperative factors. A prediction scoring system was created using the regression coefficients from the logistic regression model.
Logistic regression analysis revealed that age (β = - 0.0870; P < 0.01) and Hb (β = 0.34; P < 0.05) were significantly associated with prolonged rehabilitation programs, whereas body mass index, living alone, KSS score, and ASA class were not significantly associated with successful completion of rehabilitation programs; however, these factors contributed to the prediction scoring formula, which was defined as follows: [Formula: see text] The C-statistic for the scoring system was 0.748 (95% confidence interval, 0.672-0.824). The positive and negative likelihood ratios were 2.228 (95% CI, 1.256-3.950) and 0.386 (95% CI, 0.263-0.566), respectively. These results showed an increase of 15-20% and a decrease of 20-25% in the risk of prolonged rehabilitation. The optimal cutoff point for balancing sensitivity and specificity was 3.5, with 66.6% sensitivity and 78.0% specificity.
Older age and lower preoperative Hb were significantly associated with prolonged rehabilitation programs. We defined a new scoring formula using preoperative patient factors to predict prolonged rehabilitation utilization in patients undergoing simultaneous bilateral TKA.
康复治疗是促进双侧全膝关节置换术(TKA)后功能恢复的有效方法;然而,它被认为是医疗护理的一项重大经济负担。我们假设术前因素,包括年龄、性别、体重指数、独居、膝关节协会功能评分(KSS)、美国麻醉医师协会(ASA)分级、血红蛋白(Hb)、白蛋白水平、平均活动范围和凯尔格伦-劳伦斯分级,可预测康复治疗时间的延长。
共纳入了一家医院的191例接受双侧同期TKA的患者。成功依从组包括完成康复计划并能在术后3周内返回住所的患者(n = 132),而延迟组包括其余患者(n = 59)。使用术前因素进行逻辑回归分析。利用逻辑回归模型的回归系数创建了一个预测评分系统。
逻辑回归分析显示,年龄(β = -0.0870;P < 0.01)和Hb(β = 0.34;P < 0.05)与康复治疗时间延长显著相关,而体重指数、独居、KSS评分和ASA分级与康复计划的成功完成无显著相关性;然而,这些因素被纳入预测评分公式,定义如下:[公式:见正文]评分系统的C统计量为0.748(95%置信区间,0.672 - 0.824)。阳性和阴性似然比分别为2.228(95% CI,1.256 - 3.950)和0.386(95% CI,0.263 - 0.566)。这些结果表明康复治疗时间延长的风险增加了15 - 20%,降低了20 - 25%。平衡敏感性和特异性的最佳截断点为3.5,敏感性为66.6%,特异性为78.0%。
年龄较大和术前Hb水平较低与康复治疗时间延长显著相关。我们使用术前患者因素定义了一个新的评分公式,以预测双侧同期TKA患者康复治疗时间的延长。