Department of Public Health, College of Public Health and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.
Medicine (Baltimore). 2021 Apr 23;100(16):e25292. doi: 10.1097/MD.0000000000025292.
The research has correlated the risk factors of herpes zoster with some chronic diseases. This meta-analysis aimed to assess the incidence of herpes zoster in patients with diabetes mellitus.We conducted a literature search using Web of Science and PubMed for articles published from January 1, 2000 to December 31, 2019. The incidence rate ratio and 95% confidence interval for herpes zoster associated with diabetes mellitus was calculated.We included 5 cohort studies for a meta-analysis. The pooled incidences of herpes zoster in patients with diabetes mellitus and in patients without diabetes mellitus were 7.22 and 4.12 per 1000 person-years. The overall risk of developing herpes zoster was significantly higher in patients with diabetes mellitus when compared to those with no diabetes mellitus (incidence rate ratio = 1.60, 95% confidence interval = 1.33-1.93).Patients with diabetes mellitus are substantially at increased risk for the development of herpes zoster. Patients with diabetes mellitus should take into consideration the vaccination to prevent herpes zoster.
该研究将带状疱疹的风险因素与一些慢性病相关联。本荟萃分析旨在评估糖尿病患者带状疱疹的发病率。我们使用 Web of Science 和 PubMed 进行了文献检索，检索了 2000 年 1 月 1 日至 2019 年 12 月 31 日期间发表的文章。计算了与糖尿病相关的带状疱疹发病率比和 95%置信区间。我们纳入了 5 项队列研究进行荟萃分析。糖尿病患者和无糖尿病患者的带状疱疹累积发病率分别为每 1000 人年 7.22 例和 4.12 例。与无糖尿病患者相比，糖尿病患者发生带状疱疹的总体风险显著更高（发病率比=1.60，95%置信区间=1.33-1.93）。糖尿病患者发生带状疱疹的风险显著增加。糖尿病患者应考虑接种疫苗以预防带状疱疹。
