Spindler Nick, Ebel Franziska, Briest Susanne, Wallochny Sandra, Langer Stefan
Department of Orthopedic Surgery, Traumatology and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany.
Department of Gynecology, Women's and Children's Centre, University Hospital Leipzig, Leipzig, Germany.
Patient Prefer Adherence. 2021 Apr 13;15:741-750. doi: 10.2147/PPA.S303208. eCollection 2021.
Bilateral risk-reducing mastectomy (BRRM) can reduce the risk of developing breast cancer by up to 95% in women with increased exposure. Although survival is increased, mastectomies can adversely affect a patient physically, psychologically, and psychosexually. High health-related quality of life (HRQoL) is often achieved after simultaneous breast reconstruction (BR) following BRRM; however, data on the pre- and postoperative results of HRQoL are lacking. Therefore, we investigated the quality of life, esthetic outcome, and patient well-being after BRRM and simultaneous implant-based BR.
Of the 35 patients who underwent skin-sparing or nipple-sparing mastectomy between May 2012 and December 2017 at a university hospital, only 22 completed the evaluation. Baseline data and data on previous operations and operation techniques were retrieved from the patient's charts. BREAST-Q and short form-36 health survey (SF-36) questionnaires were used to evaluate patient satisfaction and HRQoL.
SF-36 analysis showed a significantly higher score for pain (p=0.043) in our population than in the general female population. Comparing the pre- and postoperative BREAST-Q results, a significant decrease in the physical well-being of the chest (p=0.0179) and a slight improvement in breast satisfaction were observed (p=0.3266). All patients were well-satisfied with the postoperative outcome, reconstruction, and perioperative surgeon care.
Bilateral mastectomy with simultaneous BR using pre-pectoral implants is associated with an HRQoL similar to that of the healthy population. Although bilateral mastectomy may have an immense effect on the psychological, physical, and social aspects, immediate BR preserves the outer appearance and improves self-esteem.
双侧预防性乳房切除术(BRRM)可将暴露增加的女性患乳腺癌的风险降低多达95%。虽然生存率提高了,但乳房切除术会对患者的身体、心理和性心理产生不利影响。BRRM术后同期进行乳房重建(BR)通常可实现较高的健康相关生活质量(HRQoL);然而,缺乏HRQoL术前和术后结果的数据。因此,我们调查了BRRM及同期植入式BR后的生活质量、美学效果和患者幸福感。
2012年5月至2017年12月期间在一家大学医院接受保乳或保留乳头乳房切除术的35例患者中,只有22例完成了评估。从患者病历中获取基线数据以及既往手术和手术技术的数据。使用BREAST-Q和简短健康调查36项量表(SF-36)问卷来评估患者满意度和HRQoL。
SF-36分析显示,我们研究人群的疼痛评分(p = 0.043)显著高于一般女性人群。比较BREAST-Q术前和术后结果,观察到胸部身体健康显著下降(p = 0.0179),乳房满意度略有改善(p = 0.3266)。所有患者对术后结果、重建以及围手术期外科医生的护理都非常满意。
采用胸肌前植入物同期进行BR的双侧乳房切除术与健康人群的HRQoL相似。虽然双侧乳房切除术可能对心理、身体和社会方面产生巨大影响,但即刻BR可保留外观并提高自尊。