Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 33 Badachu Road, Shijingshan District, Beijing, 100144, China.
Aesthetic Plast Surg. 2021 Oct;45(5):2409-2416. doi: 10.1007/s00266-021-02277-5. Epub 2021 Apr 22.
Once an early-stage immature scar develops into a hypertrophic scar, it is difficult to achieve satisfactory improvement with existing treatments. Therefore, the prevention of hypertrophic scar formation should be given priority. Fat grafting was previously proven to be an effective treatment for mature scars, but it has not been used in the early-stages of (less than three months) scar formation.
We present our experience with the use of combined grafting of macro fat and emulsified fat for prevention of hypertrophic scar formation in patients.
Thirty-five patients who received fat grafting for facial scar repair were included as a treatment group and another 35 patients without particular interventions were classified as the control group. Patients in both groups were followed up every three months during one year, and the Vancouver Scar Scale (VSS) was used for evaluation of the clinical outcomes at baseline (within one to three months after trauma, burn or surgery) and after 12 months of follow-up.
All patients in the treatment group achieved a marked improvement after their first fat grafting procedure. Thirteen patients (37.1%) underwent the second procedure and seven (20%) underwent the third procedure. Statistical analysis of average VSS score also showed significant differences between the treatment and control groups.
The results of this retrospective study suggest that treatment of immature scars with combined grafting of macro fat and emulsified fat can successfully prevent the formation of hypertrophic scars.
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一旦早期未成熟瘢痕发展成增生性瘢痕,现有的治疗方法很难达到令人满意的改善效果。因此,应优先考虑预防增生性瘢痕的形成。脂肪移植先前已被证明是治疗成熟瘢痕的有效方法,但尚未用于瘢痕形成的早期(<3 个月)。
我们介绍了使用大颗粒脂肪和乳化脂肪联合移植预防患者增生性瘢痕形成的经验。
将 35 例接受脂肪移植修复面部瘢痕的患者作为治疗组,另将 35 例未进行特殊干预的患者作为对照组。两组患者均在 1 年内每 3 个月随访一次,采用温哥华瘢痕量表(VSS)在基线(创伤、烧伤或手术后 1 至 3 个月内)和 12 个月随访时评估临床结果。
治疗组所有患者在首次脂肪移植后均取得显著改善。13 例患者(37.1%)进行了第二次手术,7 例患者(20%)进行了第三次手术。平均 VSS 评分的统计分析也显示治疗组和对照组之间存在显著差异。
这项回顾性研究的结果表明,用大颗粒脂肪和乳化脂肪联合移植治疗未成熟瘢痕可以成功预防增生性瘢痕的形成。
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