Center for Public Health Research, San Francisco Department of Public Health, San Francisco, CA, USA.
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
J Viral Hepat. 2021 Sep;28(9):1325-1328. doi: 10.1111/jvh.13521. Epub 2021 May 3.
Hepatitis C infections continue to rise among marginalized communities, including among transgender people. Efforts to eliminate hepatitis C from San Francisco require successful identification of active HCV infections among transgender women and subsequent treatment of infection. This secondary analysis of the National HIV Behavioral Surveillance Transgender Women (NHBS-Trans) Study aims to identify areas of improvement in the hepatitis C care cascade and associated barriers that preclude successful treatment. One hundred and eighty (89.6%) trans women reported being previously screened for HCV, 47 (26.1%) reported being diagnosed with HCV, twenty-eight of the 47 (59.6%) who reported HCV diagnosis also reported that they received HCV treatment, with and 24 of the 28 (85.7%) reported completing their treatment. Overall, we detected HCV antibodies among 23.9% of participants and detected HCV RNA among 6.0%. This suggests that despite improvements in screening for HCV, active cases may not be successfully treated. Efforts to reduce barriers to HCV care should be prioritized, with heightened consideration for trans-specific needs.
丙型肝炎感染在边缘化社区中继续上升,包括跨性别者。要想在旧金山消除丙型肝炎,就必须成功发现跨性别女性中的丙型肝炎病毒活跃感染,并对感染进行后续治疗。本项对全国艾滋病毒行为监测跨性别女性(NHBS-Trans)研究的二次分析旨在确定丙型肝炎护理链中需要改进的领域以及阻碍成功治疗的相关障碍。180 名(89.6%)跨性别女性报告称之前曾接受过丙型肝炎筛查,47 名(26.1%)报告称被诊断患有丙型肝炎,47 名报告丙型肝炎诊断的女性中,有 28 名(59.6%)报告接受了丙型肝炎治疗,28 名接受治疗的女性中,有 24 名(85.7%)报告完成了治疗。总体而言,我们在 23.9%的参与者中检测到了丙型肝炎抗体,在 6.0%的参与者中检测到了丙型肝炎病毒 RNA。这表明,尽管丙型肝炎的筛查工作有所改善,但活跃病例可能无法得到成功治疗。应优先考虑减少丙型肝炎治疗障碍的工作,并高度重视跨性别者的特殊需求。