Zhang Jing, Duan Hongzhou, Jin Haiqiang, Leng Yinglin, Chen Jing, Zhang Wei, Huang Yining
Department of Neurology, Peking University First Hospital, Beijing, China.
Department of Neurosurgery, Peking University First Hospital, Beijing, China.
Ann Palliat Med. 2021 Jul;10(7):8371-8377. doi: 10.21037/apm-20-1481. Epub 2021 Apr 15.
There are many causes of bilateral thalamic lesions, but few cases of dural arteriovenous fistula (DAVF) associated with such lesions have been reported previously. Here, we describe an adult man with reversible rapid progressive dementia (RPD) in whom bilateral thalamic lesions were caused by a DAVF that had six supply arteries and drained into both the venous sinus and cortical veins. A 53-year-old man presented with memory decline and abnormal behavior. Head computed tomography (CT) revealed insignificant low density in the bilateral thalami and high density in the right occipital lobe. Brain magnetic resonance imaging showed hyperintensities in the thalami on T2-weighted images. Magnetic resonance venogram revealed no sign of the straight sinus, but multiple tortuous vessels in the cistern of the vein of Galen. Digital subtraction angiography revealed DAVFs near the tentorium cerebelli draining into the vein of Galen, which caused the vasogenic oedema of the thalami. The patient was then treated by transarterial embolization of the feeders. He gradually recovered after the surgery. RPD with bithalamic lesions caused by DAVF is rare but reversible. Therefore, the early recognition and intervention of DAVFs is crucial for the good prognosis of patients so that fistulas can be embolized in time.
双侧丘脑病变有多种病因,但此前报道的与此类病变相关的硬脑膜动静脉瘘(DAVF)病例很少。在此,我们描述一名患有可逆性快速进展性痴呆(RPD)的成年男性,其双侧丘脑病变由一个有六条供血动脉且引流至静脉窦和皮质静脉的DAVF引起。一名53岁男性出现记忆力减退和行为异常。头部计算机断层扫描(CT)显示双侧丘脑低密度影不明显,右侧枕叶有高密度影。脑磁共振成像显示丘脑在T2加权图像上呈高信号。磁共振静脉造影显示直窦无显影,但在大脑大静脉池内有多个迂曲血管。数字减影血管造影显示小脑幕附近的DAVF引流至大脑大静脉,导致丘脑血管源性水肿。随后该患者接受了供血动脉的经动脉栓塞治疗。术后他逐渐康复。由DAVF引起的双侧丘脑病变导致的RPD很少见但可逆转。因此,早期识别和干预DAVF对患者的良好预后至关重要,以便能及时栓塞瘘管。