Ishijima B, Shimoji K, Shimizu H, Takahashi H, Suzuki I
Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Japan.
Appl Neurophysiol. 1988;51(2-5):175-87. doi: 10.1159/000099961.
Spinal and trigeminal dorsal root entry zone destruction (DREZ-tomy) was performed on 35 patients with deafferentation pain of various types. Overall, satisfactory pain relief was obtained in 65.5% of spinal DREZ-tomy cases in the follow-up observation. The result in the brachial plexus avulsion group was the best (82.4% improved), followed by the limb pain group without root avulsion (50.0%), but the truncal or visceral pain group showed the worst result (33.3%). Two patients with postherpetic trigeminal neuralgia were completely relieved of pain in the average follow-up period of 32 months, while in 2 patients with postrhizotomy facial pain, pain recurred 4 months after the operation in 1, and, in the other, pain in the medial part of the face remained unchanged. Complications were seen in about 60% of the patients, which were, however, all mild, except for 2 cases of death due to gastrointestinal disease.
对35例不同类型去传入性疼痛患者实施了脊髓和三叉神经背根入髓区毁损术(DREZ切开术)。总体而言,在随访观察中,65.5%的脊髓DREZ切开术病例获得了满意的疼痛缓解。臂丛神经撕脱伤组效果最佳(改善率82.4%),其次是无神经根撕脱的肢体疼痛组(50.0%),而躯干或内脏疼痛组效果最差(33.3%)。2例疱疹后三叉神经痛患者在平均32个月的随访期内疼痛完全缓解,而2例神经根切断术后面部疼痛患者中,1例术后4个月疼痛复发,另1例面部内侧疼痛无变化。约60%的患者出现并发症,不过除2例因胃肠疾病死亡外,均为轻度并发症。