Theisen Katherine M, Soubra Ayman, Grove Shawn, Vanni Alex J, Erickson Bradley A, Breyer Benjamin N, Myers Jeremy B, Voelzke Bryan, Broghammer Joshua A, Rourke Keith F, Alsikafi Nejd F, Buckley Jill C, Peterson Andrew C, Elliott Sean P
Mayo Clinic Rochester, MN.
University of Minnesota Minneapolis, MN.
Urology. 2021 Jul;153:320-326. doi: 10.1016/j.urology.2021.04.016. Epub 2021 Apr 24.
To determine whether ejaculatory dysfunction (EjD) and post-void dribbling (PVD) after urethroplasty are associated, providing evidence for a common etiology.
We reviewed a prospectively maintained database for first-time, anterior urethroplasties. One item from the Male Sexual Health Questionnaire (MSHQ) assessed EjD: "How would you rate the strength or force of your ejaculation". One item from the Urethral Stricture Surgery Patient-Reported Outcome Measure (USS-PROM) assessed PVD: "How often have you had slight wetting of your pants after you had finished urinating?". The frequency of symptoms was compared after penile vs. bulbar repairs, and anastomotic versus augmentation bulbar repairs. Associations were assessed with chi-square.
A total of 728 men were included. Overall, postoperative EjD and PVD were common; 67% and 66%, respectively. There was a significant association between EjD and PVD for the whole cohort (p<0.0001); this association remained significant after penile repairs (p=0.01), bulbar repairs (p<0.0007), and bulbar anastomotic repairs (p=0.002), but not after bulbar augmentation repairs (p=0.052). EjD and PVD occurred at similar rates after penile and bulbar urethroplasty. The rate of EjD was similar after bulbar augmentation and bulbar anastomotic urethroplasties, but PVD was more common after bulbar augmentation (70% vs. 52%) (p = 0.0001).
EjD and PVD after anterior urethroplasty are significantly associated with one another, supporting the theory of a common etiology. High rates after penile repairs argue against a bulbospongiosus muscle damage etiology, and high rates after anastomotic repairs argue against graft sacculation. More work is needed to better understand and prevent symptoms.
确定尿道成形术后射精功能障碍(EjD)与排尿后滴沥(PVD)是否相关,为共同病因提供证据。
我们回顾了一个前瞻性维护的首次前尿道成形术数据库。男性性健康问卷(MSHQ)中的一项评估EjD:“您如何评价射精的强度或力量”。尿道狭窄手术患者报告结局量表(USS-PROM)中的一项评估PVD:“排尿结束后,您裤子轻微潮湿的频率是多少?”。比较阴茎修复与球部修复、吻合术与扩大球部修复后症状的发生频率。采用卡方检验评估相关性。
共纳入728名男性。总体而言,术后EjD和PVD很常见,分别为67%和66%。整个队列中EjD和PVD之间存在显著相关性(p<0.0001);阴茎修复后(p=0.01)、球部修复后(p<0.0007)和球部吻合修复后(p=0.002)这种相关性仍然显著,但扩大球部修复后不显著(p=0.052)。阴茎和球部尿道成形术后EjD和PVD的发生率相似。球部扩大和球部吻合尿道成形术后EjD的发生率相似,但球部扩大后PVD更常见(70%对52%)(p = 0.0001)。
前尿道成形术后EjD和PVD彼此显著相关,支持共同病因理论。阴茎修复后发生率高与球海绵体肌损伤病因相悖,吻合修复后发生率高与移植物成囊病因相悖。需要更多工作来更好地理解和预防这些症状。