Hiraki Masatsugu, Tanaka Toshiya, Sadashima Eiji, Sato Hirofumi, Kitahara Kenji
Department of Surgery, Saga Medical Center Koseikan, 400 Nakabaru, Kasemachi, Saga City, Saga, 840-8571, Japan.
Life Science Research Institution, Saga Medical Center Koseikan, 400 Nakabaru, Kasemachi, Saga City, Saga, 840-8571, Japan.
Int J Colorectal Dis. 2021 Sep;36(9):1853-1859. doi: 10.1007/s00384-021-03938-2. Epub 2021 Apr 27.
Urinary retention (UR) is a frequent complication following laparoscopic colorectal surgery. The aim of the present study was to investigate the risk factors for acute UR after laparoscopic surgery for colorectal cancer in patients receiving epidural analgesia.
A retrospective study was conducted of 201 patients who underwent laparoscopic surgery for colorectal cancer among those receiving epidural analgesia. Univariate and multivariate analyses were performed to determine the clinicopathological factors associated with acute UR. Acute UR was defined as Clavien-Dindo classification grade ≥ 1.
The overall incidence of acute UR was 17.9% (36/201). The univariate analysis showed that male gender (P = 0.043), a history of chronic heart failure (P = 0.009), an increased level of serum creatinine (P = 0.028), an increased intraoperative fluid volume (P = 0.016), and an early postoperative date of urinary catheter removal (P = 0.003) were both associated with acute UR. The multivariate logistic regression analysis revealed an increased intraoperative fluid volume (100-ml increments; odds ratio [OR]: 1.085, 95% confidence interval [CI]: 1.034-1.138, P < 0.001), history of chronic heart failure (OR: 6.843, 95% CI: 1.893-24.739, P = 0.003), and postoperative date of urinary catheter removal (OR: 0.550, 95% CI: 0.343-0.880, P = 0.013) were independent risk factors for acute UR.
Our findings suggest that an increased intraoperative fluid volume, history of chronic heart failure, and early removal of the urinary catheter are risk factors of UR after laparoscopic surgery for colorectal cancer in patients receiving epidural analgesia. An assessment using these factors might be helpful for predicting acute UR.
尿潴留(UR)是腹腔镜结直肠手术后常见的并发症。本研究旨在探讨接受硬膜外镇痛的结直肠癌患者腹腔镜手术后急性尿潴留的危险因素。
对201例接受硬膜外镇痛的结直肠癌腹腔镜手术患者进行回顾性研究。进行单因素和多因素分析以确定与急性尿潴留相关的临床病理因素。急性尿潴留定义为Clavien-Dindo分级≥1级。
急性尿潴留的总体发生率为17.9%(36/201)。单因素分析显示,男性(P = 0.043)、慢性心力衰竭病史(P = 0.009)、血清肌酐水平升高(P = 0.028)、术中液体量增加(P = 0.016)以及术后早期拔除导尿管(P = 0.003)均与急性尿潴留相关。多因素logistic回归分析显示,术中液体量增加(每增加100 ml;比值比[OR]:1.085,95%置信区间[CI]:1.034 - 1.138,P < 0.001)、慢性心力衰竭病史(OR:6.843,95% CI:1.893 - 24.739,P = 0.003)以及术后导尿管拔除时间(OR:0.550,95% CI:0.343 - 0.880,P = 0.013)是急性尿潴留的独立危险因素。
我们的研究结果表明,术中液体量增加、慢性心力衰竭病史以及早期拔除导尿管是接受硬膜外镇痛的结直肠癌患者腹腔镜手术后尿潴留的危险因素。利用这些因素进行评估可能有助于预测急性尿潴留。