神经性厌食症中的情绪与直立性去甲肾上腺素反应

Mood and orthostatic norepinephrine response in anorexia nervosa.

作者信息

Laessle R G, Schweiger U, Pirke K M

机构信息

Max-Planck-Institute of Psychiatry, Division of Psychoneuroendocrinology, Munich, F.R.G.

出版信息

Psychiatry Res. 1988 Apr;24(1):87-94. doi: 10.1016/0165-1781(88)90144-8.

DOI:10.1016/0165-1781(88)90144-8

PMID:3393619

Abstract

The relationship between mood and noradrenergic activity, measured by orthostatic norepinephrine response (delta NE), was investigated in 24 patients with anorexia nervosa during inpatient treatment. Mood and delta NE correlated significantly at four out of five measurement points. Group comparisons identified significantly worse mood in patients with pathologically low delta NE values. Thus, biological consequences of altered eating behavior may also affect such psychological symptoms as depressed mood.

摘要

在24名神经性厌食症住院患者中，研究了通过直立性去甲肾上腺素反应（ΔNE）测量的情绪与去甲肾上腺素能活性之间的关系。在五个测量点中的四个点上，情绪与ΔNE显著相关。组间比较发现，ΔNE值病理性降低的患者情绪明显更差。因此，饮食行为改变的生物学后果也可能影响诸如情绪低落等心理症状。