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带孔腹主动脉瘤腔内修复装置的外科取出术并发主动脉肠瘘

Surgical Explantation of a Fenestrated Endovascular Abdominal Aortic Aneurysm Repair Device Complicated by Aorto-Enteric Fistula.

作者信息

Caradu Caroline, Vosgin-Dinclaux Valérian, Lakhlifi Emilie, Dubuisson Vincent, Ducasse Eric, Bérard Xavier

机构信息

Vascular Surgery Department, Bordeaux University Hospital, Bordeaux, France.

出版信息

EJVES Vasc Forum. 2020 Dec 19;50:12-18. doi: 10.1016/j.ejvsvf.2020.12.020. eCollection 2021.

Abstract

INTRODUCTION

Alarming outcomes have been reported following infected endovascular aortic aneurysm repair (EVAR) device explantation. Infected fenestrated EVAR (FEVAR) exposes patients to even worse procedural risks.

REPORT

A 67 year old man with a prior history of FEVAR presented with impaired general condition, abdominal and back pain, and increased C reactive protein. Computed tomography angiography revealed a collection around the aortic graft bifurcation and F-fluorodeoxyglucose-positron emission tomography (FDG-PET) revealed increased FDG uptake at this level, confirmed by labelled white blood cells, all favouring graft infection. A thoracophrenolumbotomy was performed and revealed an aorto-enteric fistula which was treated by small bowel resection. The left renal artery was transected at the distal end of the bridging stent and a thoracorenal bypass was performed. The thoracic aorta was cross clamped above the coeliac trunk for complete graft excision. Meanwhile, the right kidney was perfused with 4°C Ringer lactate solution. reconstruction was accomplished with a bifurcated antimicrobial graft sutured below the superior mesenteric artery with re-implantation of the right renal artery. The patient was left with a laparostomy for definitive abdominal closure, restoration of the digestive tract, and omental wrap 72 hours later. Broad spectrum antibiotic therapy was initiated peri-operatively and reduced to sulfamethoxazole/trimethoprim for a total duration of six weeks after one sample was positive for Eleven months later, the patient was free from re-infection, with no fever or inflammatory syndrome.

DISCUSSION

Total explantation of stent grafts with tissue debridement and post-operative antibiotic therapy is the gold standard when dealing with infected EVAR. As with type IV thoraco-abdominal aneurysm open repair, FEVAR device explantation requires additional protective measures to prevent visceral ischaemia and renal impairment. In agreement with the European Society for Vascular Surgery guidelines, such patients should be referred to dedicated vascular centres with expertise in surgical repair, anaesthetics, and post-operative intensive care.

摘要

引言

感染性血管内主动脉瘤修复术(EVAR)器械取出术后报告了令人担忧的结果。感染性开窗EVAR(FEVAR)使患者面临更严重的手术风险。

报告

一名有FEVAR病史的67岁男性,全身状况受损,伴有腹部和背部疼痛,C反应蛋白升高。计算机断层血管造影显示主动脉移植物分叉处有积液,F-氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)显示该水平FDG摄取增加,经标记白细胞证实,均提示移植物感染。行胸腹腰联合切口,发现主动脉肠瘘,行小肠切除术治疗。在桥接支架远端切断左肾动脉,并行胸肾旁路手术。在腹腔干上方夹闭胸主动脉以完整切除移植物。同时,用4℃乳酸林格液灌注右肾。用分叉抗菌移植物在肠系膜上动脉下方缝合,重新植入右肾动脉完成重建。患者留置剖腹切口,72小时后进行确定性腹部闭合、消化道重建和网膜包裹。围手术期开始使用广谱抗生素治疗,一个样本对[具体细菌名称未给出]呈阳性后,抗生素减至磺胺甲恶唑/甲氧苄啶,共持续六周。11个月后,患者无再次感染,无发热或炎症综合征。

讨论

在处理感染性EVAR时,带组织清创的支架移植物全取出术及术后抗生素治疗是金标准。与IV型胸腹主动脉瘤开放修复一样,FEVAR器械取出术需要额外的保护措施以防止内脏缺血和肾功能损害。根据欧洲血管外科学会指南,此类患者应转诊至在手术修复、麻醉和术后重症监护方面有专业知识的专门血管中心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1d/8077032/3c98575e006b/gr1.jpg

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