Department of Internal Medicine, Alameda Health System - Highland Hospital, Oakland, CA.
Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Skinmed. 2021 Apr 1;19(2):150-154. eCollection 2021.
A 37-year-old man with a history of renal transplantation in 2013 due to focal segmental glomerulosclerosis presented to the emergency room with a 2-week history of fever, chills, anorexia, weight loss, abdominal pain, diarrhea, and a new asymptomatic lesion on the right side of the neck. The patient worked as a truck driver and frequently traveled to Wisconsin; he had not traveled internationally in the past year. He lived with his brother who had a pet cat. He was compliant with his anti-rejection medication regimen, which included mycophenolate mofetil, tacrolimus, and prednisone. Physical examination of the neck revealed an 8-mm exophytic, friable, red papule with overlying blood crusts (Figure 1). The remainder of the mucocutaneous examination was unremarkable, and there was no palpable lymphadenopathy. The patient was started on empiric intravenous cefepime and metronidazole and admitted to the hospital for further management. A punch biopsy of the lesion was performed.
一位 37 岁男性,2013 年因局灶节段性肾小球硬化症接受了肾移植,因发热、寒战、厌食、体重减轻、腹痛、腹泻和右侧颈部出现新的无症状性皮损,于急诊就诊。该患者是一名卡车司机,经常前往威斯康星州;过去一年他没有出过国。他与养了一只宠物猫的哥哥住在一起。他一直遵医嘱服用抗排异药物,包括霉酚酸酯、他克莫司和泼尼松。颈部体格检查发现一个 8mm 的外生性、易碎、红色丘疹,伴有覆盖的血痂(图 1)。其余黏膜皮肤检查未见异常,无可触及的淋巴结肿大。患者开始接受经验性静脉注射头孢吡肟和甲硝唑,并入院进一步治疗。对皮损进行了打孔活检。