Department of Congenital and Pediatric Heart Surgery, 14924German Heart Center Munich, Technical University of Munich, School of Medicine, Munich, Germany.
Institute for Translational Cardiac Surgery (INSURE), 14924German Heart Center Munich, Technical University of Munich, School of Medicine, Munich, Germany.
World J Pediatr Congenit Heart Surg. 2021 May;12(3):344-351. doi: 10.1177/2150135121990651.
Long-term morbidity and mortality outcomes of the arterial switch operation (ASO) in patients with transposition of the great arteries and Taussig-Bing anomaly are excellent. With an increasing number of patients reaching adolescence and adulthood, more attention is directed toward quality of life. Our study aimed to determine the health-related quality of life (hrQoL) outcomes in patients after the ASO and identify factors influencing their hrQoL.
In this cross-sectional study, hrQoL of patients after ASO was assessed with the German version of the Short Form-36 (SF-36) and the potential association of specified clinical factors was analyzed. Patients of at least 14 years of age who underwent ASO in our institution from 1983 were considered eligible.
Of the 355 questionnaires sent to eligible patients, 261 (73%) were available for analysis. Compared to the reference population, patients who had undergone ASO had a significantly higher score in all subscales of the SF-36 except for vitality ( < .01). Patients with an implanted pacemaker ( = .002), patients who required at least one reoperation ( < .001), and patients currently taking cardiac medication ( < .004) or oral anticoagulation ( = .036) had lower physical component scores compared to patients without these factors.
Patients' self-assessed and self-reported hrQoL after ASO (using German version of the Short Form 36) is very good. In this population, hrQoL is influenced by reoperation, the need for a pacemaker, and current cardiac medication or anticoagulant use. The development of strategies designed to mitigate or minimize the requirements for, and/or impact of these factors may lead to better hrQoL in this patient population.
大动脉转位（TGA）合并永存动脉干（TAP）患者行大动脉调转术（ASO）后，长期的发病率和死亡率结果非常好。随着越来越多的患者进入青少年和成年期，人们越来越关注生活质量。我们的研究旨在确定 ASO 后患者的健康相关生活质量（HRQoL）结果，并确定影响其 HRQoL 的因素。
在这项横断面研究中，使用德国版 36 项简短健康调查问卷（SF-36）评估 ASO 后患者的 HRQoL，并分析特定临床因素的潜在关联。我们将在本机构接受 ASO 治疗且年龄至少 14 岁的患者视为符合条件。
在发送给符合条件的患者的 355 份问卷中，有 261 份（73%）可用于分析。与参考人群相比，接受 ASO 的患者除活力外（<0.01），SF-36 的所有子量表评分均显著较高。与无这些因素的患者相比，植入起搏器的患者（=0.002）、至少需要一次再次手术的患者（<0.001）、目前服用心脏药物（<0.004）或口服抗凝剂（=0.036）的患者的生理成分评分较低。
患者自我评估和报告的 ASO 后 HRQoL（使用德国版 36 项简短健康调查问卷）非常好。在该人群中，HRQoL 受到再次手术、起搏器需求以及当前心脏药物或抗凝剂使用的影响。制定旨在减轻或最小化这些因素的需求和/或影响的策略可能会改善该患者群体的 HRQoL。
Zotero 插件