自服安全性杀虫剂中毒：吡虫啉中毒病例系列。
Self-Poisoning With Safer Insecticide: A Case Series on Imidacloprid Poisoning.
机构信息
From the Department of Forensic Medicine and Toxicology, AIIMS Bhubaneswar, Odisha.
Department of Forensic Medicine and Toxicology, IMS and SUM Hospital, Bhubaneswar, Odisha, India.
出版信息
Am J Forensic Med Pathol. 2022 Mar 1;43(1):66-68. doi: 10.1097/PAF.0000000000000685.
Imidacloprid (IMI) is a systemic insecticide that belongs to the neonicotinoid group of insecticides. It is highly effective against sucking, boring, and root-feeding insects. Besides, it has a favorable toxicological profile on humans. Currently, IMI is the largest selling insecticide in the world by replacing organophosphates and carbamates. It acts as nicotinic acetylcholine receptor agonist in the central nervous system of insects. To date, there is no specific antidote available for IMI poisoning. Despite a better safety profile on humans, severe toxicity from IMI poisoning is not uncommon. Here, we report a series of 4 cases who were admitted to our tertiary care center with a history of IMI poisoning.
吡虫啉（IMI）是一种内吸性杀虫剂，属于新烟碱类杀虫剂。它对刺吸式口器、蛀食性和根食性昆虫有极高的防治效果。此外，它对人类具有良好的毒理学特性。目前，吡虫啉取代有机磷和氨基甲酸酯类杀虫剂，成为世界上销量最大的杀虫剂。它在昆虫的中枢神经系统中作为烟碱型乙酰胆碱受体激动剂起作用。迄今为止，尚无针对吡虫啉中毒的特效解毒剂。尽管对人类的安全性更好，但吡虫啉中毒的严重毒性并不少见。在这里，我们报告了 4 例因吡虫啉中毒而入住我们三级治疗中心的病例。
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