中枢神经系统血管内淋巴瘤导致快速进展性痴呆。
Central nervous system intravascular lymphoma leading to rapidly progressive dementia.
作者信息
Turin Christie G, Ting Kevin, Bradshaw Anthony, Dunham S Richard, Nunez-Wallace Karen, Patel Shital M, Dangayach Priti, Holdener Stephanie, Lin Weei-Chin
机构信息
Department of Medicine, Baylor College of Medicine, Houston, Texas.
Department of Neurology, Baylor College of Medicine, Houston, Texas.
出版信息
Proc (Bayl Univ Med Cent). 2021 Jan 11;34(3):373-375. doi: 10.1080/08998280.2020.1866943.
Intravascular lymphoma is an uncommon subtype of B-cell lymphoma with neoplastic cells limited to the lumen of small blood vessels. We report a case of a 52-year-old man who presented with constitutional symptoms and rapidly progressive dementia. He was found to have diffuse leptomeningeal and faint parenchymal enhancement on magnetic resonance imaging and was subsequently diagnosed with intravascular lymphoma following a brain biopsy. He responded remarkably well to systemic and intrathecal chemotherapy. The diagnosis and treatment of intravascular lymphoma have been guided by a few case reports and are largely based on expert opinion.
血管内淋巴瘤是B细胞淋巴瘤的一种罕见亚型，肿瘤细胞局限于小血管腔内。我们报告一例52岁男性患者，其出现全身症状和快速进展性痴呆。磁共振成像显示他有弥漫性软脑膜和轻微的实质强化，随后经脑活检诊断为血管内淋巴瘤。他对全身和鞘内化疗反应良好。血管内淋巴瘤的诊断和治疗一直以少数病例报告为指导，且很大程度上基于专家意见。
Zotero 插件