极低出生体重儿的成熟里程碑的实现。
Achievement of maturational milestones among very low birth weight infants.
机构信息
Department of Pediatrics, Division of Neonatology, University of Virginia School of Medicine, Charlottesville, VA, USA.
University of Virginia School of Medicine, Charlottesville, VA, USA.
出版信息
J Neonatal Perinatal Med. 2022;15(1):155-163. doi: 10.3233/NPM-200698.
BACKGROUND
Very low birth weight (VLBW) infants must achieve several maturational milestones to be discharged home from the NICU.
OBJECTIVE
Describe the timing of maturational milestones in VLBW infants and the impact of clinical variables and milestone achievement on postmenstrual age (PMA) at discharge.
METHODS
For VLBW infants without severe lung disease discharged home from a level IV NICU, we assessed PMA at the achievement of thermoregulation, cardiorespiratory stability, feeding, and discharge.
RESULTS
In 400 infants (median GA 28.4 weeks), lower birth weight, white race, and having multiple comorbidities of prematurity predicted later discharge PMA. The most common milestone sequence was CPAP discontinuation, caffeine discontinuation, thermoregulation, apnea resolution, and full oral feeds. PMA at apnea resolution and full oral feeds correlated highly with discharge PMA.
CONCLUSIONS
In a single-center VLBW cohort, comorbidities of prematurity impacted the timing of NICU discharge through delay in oral feeding and cardiorespiratory stability.
背景
极低出生体重（VLBW）婴儿必须达到几个成熟里程碑才能从新生儿重症监护病房（NICU）出院回家。
目的
描述 VLBW 婴儿成熟里程碑的时间以及临床变量和里程碑达成情况对出院时校正胎龄（PMA）的影响。
方法
对于没有严重肺部疾病且从四级 NICU 出院回家的 VLBW 婴儿，我们评估了体温调节、心肺稳定性、喂养和出院时达到的 PMA。
结果
在 400 名婴儿（中位胎龄 28.4 周）中，较低的出生体重、白种人以及存在多种早产儿合并症预测了较晚的出院 PMA。最常见的里程碑序列是 CPAP 停用、咖啡因停用、体温调节、呼吸暂停缓解和完全口服喂养。呼吸暂停缓解和完全口服喂养时的 PMA 与出院时的 PMA 高度相关。
结论
在单中心 VLBW 队列中，早产儿的合并症通过延迟口服喂养和心肺稳定性影响 NICU 出院时间。
Zotero 插件