Suvorov N F, Gulyakov M B
Pavlov Institute of Physiology, U.S.S.R. Academy of Sciences, Leningrad.
Int J Psychophysiol. 1988 Jun;6(2):91-7. doi: 10.1016/0167-8760(88)90040-2.
The instrumental differentiation of left-right positions of sound-conditioned stimuli (series of clicks under dichotic stimulation) in 8 dogs was examined before and after the bilateral electrolytic lesions of various parts of the caudate nucleus (NCd). It was demonstrated that after damage of the NCd the correct differentiation of the side of monaural sound stimulation was preserved in all dogs. However, the differentiation of lateralization of sound produced by interaural time differences was selectively impaired. Lesions of the dorsal part of the NCd heads caused the absolute absence of the differentiation of the binaural sound image lateralization for 21-50 days after the operation. This function partially recovered but the percentage of correct responses remained significantly reduced in comparison with preoperative performance. Lesions of the ventral segment of the NCd heads of different parts of the NCd bodies had less influence on the performance of this behavioral task. In these cases there was no period of absolute absence of the differentiation, but the level of correct responses to the binaural signals was significantly reduced. It is suggested that the NCd is a part of the system of brain structures in which the parameters of the conditioned sound signals are compared with a reference system for recognition of sound location. The result of this comparison is used by the NCd for choosing a corresponding program of the motor response.
在对8只狗双侧电解损毁尾状核（NCd）各部位之前和之后，检测了它们对声音条件刺激（双耳分听刺激下的一系列滴答声）左右位置的工具性辨别能力。结果表明，损毁NCd后，所有狗对单耳声音刺激侧的正确辨别能力得以保留。然而，由双耳时间差异产生的声音定位辨别能力却受到了选择性损害。损毁NCd头部的背侧部分导致术后21至50天双耳声像定位辨别能力完全缺失。该功能部分恢复，但与术前表现相比，正确反应的百分比仍显著降低。损毁NCd头部腹侧段以及NCd体部不同部位对这一行为任务的表现影响较小。在这些情况下，不存在辨别能力完全缺失的时期，但对双耳信号的正确反应水平显著降低。研究表明，NCd是脑结构系统的一部分，在该系统中，条件声音信号的参数与用于识别声音位置的参考系统进行比较。NCd利用这种比较的结果来选择相应的运动反应程序。
