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玻璃体切割术治疗枪击伤所致眼后段眼内异物残留的长期预后

Long-Term Outcome of Pars Plana Vitrectomy for Retained Posterior Segment Intraocular Foreign Body Secondary to Gunshot Injury.

作者信息

Ghoraba Hammouda Hamdy, Leila Mahmoud, Zaky Adel Galal, Elgouhary Sameh Mohamed, Ellakwa Amin Faisal, Mansour Hosam Othman, Heikal Mohamed Amin

机构信息

Faculty of Medicine, Tanta University, Tanta, Egypt.

Magrabi Eye Hospital, Tanta, Egypt.

出版信息

Clin Ophthalmol. 2021 May 6;15:1897-1904. doi: 10.2147/OPTH.S311163. eCollection 2021.

Abstract

PURPOSE

To report the long-term outcome of pars plana vitrectomy (PPV) for management of retained posterior segment intraocular foreign body (IOFB) secondary to gunshot injury.

METHODS

This is a retrospective interventional case series including consecutive patients who had PPV for retained posterior segment IOFB secondary to gunshot injury. Main outcome measures were final best-corrected visual acuity (BCVA), long-term globe survival and detection of complications. Spearman correlation analyzed relationships between numerical data. Kruskal-Wallis test compared differences in initial BCVA and final BCVA across variables. Categorical variables were tested using Chi square or Fisher's exact test. P value is significant at 0.05.

RESULTS

The study included 103 eyes of 103 patients. Mean baseline BCVA was 0.01 decimal unit (2 logMAR). Mean duration from primary repair to PPV was 3 weeks. Mean duration of post-operative follow-up was 60 months. Mean final BCVA was 0.04 decimal unit (1.3 logMAR), p 0.001. Post-operatively, BCVA improved in 58.2% of patients. Nineteen patients (18%) gained ≥2 lines of vision, and 15 patients (14.5%) achieved final BCVA of 0.4 decimal unit (logMAR 0.4). All complications were related to the original injury. These included macular scar (19%), macular pucker (6%), recurrent retinal detachment (4%), subretinal fibrosis (3%), consecutive optic atrophy (3%), and PVR (3%). Phthisis bulbi or sympathetic ophthalmia did not develop in any case.

CONCLUSION

PPV for removal of IOFB caused by gunshot injury yielded long-term favorable functional outcome with excellent globe survival. Poor initial BCVA, location of IOFB in the posterior pole, associated lens injury and retinal detachment are significant adverse prognostic factors for final BCVA but not for globe survival.

摘要

目的

报告经平坦部玻璃体切除术(PPV)治疗枪伤所致后段眼内异物(IOFB)残留的长期疗效。

方法

这是一项回顾性干预病例系列研究,纳入了因枪伤导致后段IOFB残留而接受PPV治疗的连续患者。主要观察指标为最终最佳矫正视力(BCVA)、长期眼球存活情况及并发症的检测。Spearman相关性分析数值数据之间的关系。Kruskal-Wallis检验比较各变量初始BCVA和最终BCVA的差异。分类变量采用卡方检验或Fisher精确检验。P值在0.05时具有统计学意义。

结果

该研究纳入了103例患者的103只眼。平均基线BCVA为0.01小数视力(2 logMAR)。从初次修复到PPV的平均时间为3周。术后平均随访时间为60个月。平均最终BCVA为0.04小数视力(1.3 logMAR),p<0.001。术后,58.2%的患者BCVA有所改善。19例患者(18%)视力提高≥2行,15例患者(14.5%)最终BCVA达到0.4小数视力(logMAR 0.4)。所有并发症均与原发损伤有关。这些并发症包括黄斑瘢痕(19%)、黄斑皱襞(6%)、复发性视网膜脱离(4%)、视网膜下纤维化(3%)、连续性视神经萎缩(3%)和增殖性玻璃体视网膜病变(3%)。未发生眼球痨或交感性眼炎。

结论

PPV治疗枪伤所致IOFB残留可获得长期良好的功能预后及出色的眼球存活率。初始BCVA差、IOFB位于后极部、合并晶状体损伤和视网膜脱离是影响最终BCVA的重要不良预后因素,但不影响眼球存活。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2f/8110266/6644653297e8/OPTH-15-1897-g0001.jpg

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