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肥胖患者行减重手术的术前处理:内镜和幽门螺杆菌根除的作用。

Preoperative management of obese patients undergoing bariatric surgery: Role of endoscopy and Helicobacter eradication.

机构信息

Basic Health Science Department, Health Science Faculty, Universidad Rey Juan Carlos, Alcorcón (Madrid), Spain.

Department of Surgery, Universidad Rey Juan Carlos, Alcorcón (Madrid), Spain.

出版信息

Obes Res Clin Pract. 2021 May-Jun;15(3):289-290. doi: 10.1016/j.orcp.2021.05.002. Epub 2021 May 13.

DOI:10.1016/j.orcp.2021.05.002
PMID:33992573
Abstract

BACKGROUND

Obesity is a pandemic disease associated to severe health problems. Management is usually multimodal, but many patients eventually need surgery to reduce weight. Many guidelines recommend endoscopy prior to surgery. This study reviews a series of patients undergoing sleeve gastrectomy to see whether endoscopy performance and histopathological findings influence surgery outcome.

MATERIAL AND METHODS

Retrospective series of patients undergoing sleeve gastrectomy as bariatric procedure at a single institution. We have reviewed the demographic data, the associated pathologies, endoscopic findings prior to surgery, histopathological findings in the surgical resection specimen and postoperative complication rate.

RESULTS

259 patients fulfilled criteria for the study. Over 70% were women and the mean age was 46.9 (SD 9.8). Preoperative endoscopy was performed in 28.9% of the patients and biopsy only in 19.3%. Helicobacter pylori was detected in 28% of the patients undergoing endoscopy (either in the biopsy or the urease test) and eradicated before surgery in all the patients. Helicobacter pylori was present in 9.7% of the surgical resection specimens and its presence was significantly associated with the development of postoperative complications, mostly staple line leaks (p = 0.01).

CONCLUSION

Our study confirms that Helicobacter infection is significantly associated with postoperative complications after sleeve gastrectomy. It is therefore important to detect its presence and eradicate it before surgery.

摘要

背景

肥胖是一种与严重健康问题相关的流行疾病。管理通常是多模式的,但许多患者最终需要手术来减肥。许多指南建议在手术前进行内镜检查。本研究回顾了一系列接受袖状胃切除术的患者,以观察内镜检查表现和组织病理学发现是否影响手术结果。

材料和方法

这是一项在单家机构进行的袖状胃切除术作为减重手术的回顾性系列患者研究。我们回顾了人口统计学数据、相关病理、术前内镜检查结果、手术切除标本的组织病理学发现和术后并发症发生率。

结果

259 名患者符合研究标准。超过 70%为女性,平均年龄为 46.9(标准差 9.8)。28.9%的患者进行了术前内镜检查,仅 19.3%进行了活检。在接受内镜检查的患者中(无论是活检还是尿素酶试验),有 28%检测到幽门螺杆菌,并在所有患者中均在术前根除。幽门螺杆菌在 9.7%的手术切除标本中存在,其存在与术后并发症的发生显著相关,主要是吻合口漏(p = 0.01)。

结论

我们的研究证实,幽门螺杆菌感染与袖状胃切除术后的并发症显著相关。因此,在手术前检测并根除幽门螺杆菌非常重要。

相似文献

1
Preoperative management of obese patients undergoing bariatric surgery: Role of endoscopy and Helicobacter eradication.肥胖患者行减重手术的术前处理:内镜和幽门螺杆菌根除的作用。
Obes Res Clin Pract. 2021 May-Jun;15(3):289-290. doi: 10.1016/j.orcp.2021.05.002. Epub 2021 May 13.
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Preoperative Helicobacter pylori Screening and Treatment in Patients Undergoing Laparoscopic Sleeve Gastrectomy.腹腔镜袖状胃切除术患者术前幽门螺杆菌筛查和治疗。
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Does Helicobacter pylori infection influence the major postoperative complication rate after sleeve gastrectomy? A retrospective cohort study in an endemic region.幽门螺杆菌感染是否会影响袖状胃切除术后的主要并发症发生率?一项在地方性流行地区开展的回顾性队列研究。
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Histopathology Findings in Patients Undergoing Laparoscopic Sleeve Gastrectomy.腹腔镜袖状胃切除术患者的组织病理学发现。
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The impact of preoperative investigations on the management of bariatric patients; results of a cohort of more than 1200 cases.术前检查对肥胖症患者管理的影响:超过 1200 例患者的队列研究结果。
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Can Helicobacter pylori Eradication Treatment Modify the Metabolic Response to Bariatric Surgery?幽门螺杆菌根除治疗能否改变减重手术的代谢反应?
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引用本文的文献

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IMPACT OF HELICOBACTER PYLORI ON EARLY POSTOPERATIVE COMPLICATIONS AFTER SLEEVE GASTRECTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS.幽门螺杆菌对袖状胃切除术后早期并发症的影响:系统评价和荟萃分析。
Arq Bras Cir Dig. 2024 Feb 2;36:e1788. doi: 10.1590/0102-672020230070e1788. eCollection 2024.