Department of Occupational therapy, Faculty of Health Science, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Department of Neurosurgery, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Brain Cogn. 2021 Jul;151:105752. doi: 10.1016/j.bandc.2021.105752. Epub 2021 May 14.
The frontal aslant tract (FAT) mainly connects the supplementary motor area (SMA) and inferior frontal gyrus. The left FAT is involved in language-related functions, while the functional role of the right FAT is not fully understood. The aim of this study was to investigate the function of the right FAT by dividing it into three segments according to the anatomical structure. A total of 34 right frontal gliomas who had undergone surgery were studied. Participants were assessed for the acute and chronic phases of several neuropsychological and motor functions. FAT was reconstructed into the anterior, middle, and posterior segments according to the cortical connections as the medial prefrontal cortex, pre-SMA, and SMA proper, respectively. The relationships between the damaged severity of each FAT segment and behavioral scores were analyzed. A significant relationship was observed only in the acute phase motor function and posterior segment of the FAT. The middle segment was involved in motor function, but it did not have a sufficient significance level compared to the posterior segment. Our study revealed that the right FAT can be divided into three segments and that its posterior segment is related to acute phase motor function.
额斜前束（FAT）主要连接辅助运动区（SMA）和额下回。左侧 FAT 与语言相关功能有关，而右侧 FAT 的功能尚不完全清楚。本研究旨在通过根据解剖结构将其分为三个节段来研究右侧 FAT 的功能。共研究了 34 例接受手术治疗的右侧额叶胶质瘤患者。通过神经心理学和运动功能的急性和慢性阶段评估参与者。根据皮质连接，将 FAT 重建为前、中、后三个节段，分别对应于内侧前额叶皮质、前 SMA 和 SMA 区。分析了每个 FAT 节段损伤严重程度与行为评分之间的关系。仅在急性运动功能和 FAT 的后段观察到显著相关性。中间段与运动功能有关，但与后段相比，其显著性水平不足。我们的研究表明，右侧 FAT 可以分为三个节段，其后段与急性运动功能有关。
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