Brasey D L, Fankhauser H, de Tribolet N
Service de neurochirurgie, CHUV, Lausanne.
Schweiz Med Wochenschr. 1988 Jun 18;118(24):919-23.
The results of ventriculo-atrial shunting have been analyzed in 37 patients with normal pressure hydrocephalus. The nature and severity of the symptoms and their progression in time, together with the results of computed tomography and clinical response to CSF withdrawal by lumbar puncture, were compared with the outcome after shunting, in order to define reliable prognostic criteria. In the long term, 43% of the patients improved and 30% died. The complication rate was 22%, including primarily subdural hematoma and shunt malfunction. Amongst the symptoms, ataxia responded best to shunting. Clinical improvement after subtraction of lumbar CSF, and demonstration by computed tomography of ventricular dilation with a hypodense area around the frontal horns in the absence of cortical atrophy, were associated with a favorable outcome.
对37例正常压力脑积水患者的脑室-心房分流术结果进行了分析。将症状的性质、严重程度及其随时间的进展,以及计算机断层扫描结果和腰椎穿刺脑脊液引流的临床反应,与分流术后的结果进行比较,以确定可靠的预后标准。从长期来看,43%的患者病情改善,30%的患者死亡。并发症发生率为22%,主要包括硬膜下血肿和分流装置故障。在各种症状中,共济失调对分流术反应最佳。腰椎脑脊液引流后临床改善,以及计算机断层扫描显示脑室扩张且额角周围有低密度区而无皮质萎缩,与良好预后相关。