Sexual Behaviours Clinic, Integrated Forensic Program, Royal Ottawa Mental Health Centre, Ottawa, Ontario, Canada.
Department of Psychology and Department of Criminology, University of Ottawa, Ottawa, Ontario, Canada.
Prim Care Companion CNS Disord. 2021 Feb 18;23(1):20br02663. doi: 10.4088/PCC.20br02663.
Pramipexole is a dopaminergic pharmacologic agent with reported adverse effects that include hypersexuality, shift in sexual interests, pathological gambling, compulsive shopping, and binge eating. Pramipexole is indicated in the treatment of Parkinson's disease and restless leg syndrome and has been used as adjunctive or add-on treatment in major depressive disorder. This report describes the successful treatment of a series of 4 adult men who presented with concerns about problematic sexual interests and behaviors that began after treatment with pramipexole related to Parkinson's disease or restless leg syndrome.
普拉克索是一种多巴胺能药物,有报道称其不良反应包括性欲亢进、性兴趣改变、病理性赌博、强迫性购物和暴食。普拉克索用于治疗帕金森病和不安腿综合征,并已被用作重性抑郁障碍的辅助或附加治疗。本报告描述了成功治疗 4 名成年男性的一系列病例,这些患者在因帕金森病或不安腿综合征接受普拉克索治疗后出现了与性兴趣和性行为相关的问题,并对此表示担忧。