Department of Obstetrics, Gynecology and Women's Health, University of Minnesota School of Medicine, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
Department of Obstetrics, Gynecology and Women's Health, University of Minnesota School of Medicine, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
Pregnancy Hypertens. 2021 Aug;25:1-6. doi: 10.1016/j.preghy.2021.04.001. Epub 2021 Apr 20.
Improve appropriate and timely administration of rapid acting antihypertensive medication for the management of hypertensive emergency in pregnancy with utilization of an automated electronic health record (EHR) alert in an academic birthplace.
An automated alert was incorporated into an existing EHR that notified providers of a documented severe range blood pressure, defined as systolic blood pressure (SBP) ≥ 160 mmHg or diastolic blood pressure (DBP) ≥ 110 mmHg. Retrospective chart review was utilized to evaluate appropriate intervention before and after implementation of the alert (referred to as pre-implementation and post-implementation cohorts).
The primary outcome was appropriate administration of rapid-acting antihypertensive medication for the management of hypertensive emergency. Secondary outcomes included: appropriate administration of intravenous (IV) magnesium sulfate for seizure prophylaxis, initiation of oral antihypertensive medication postpartum, and appropriate timing of follow up for blood pressure evaluation following discharge.
Of 98 patients identified as having hypertensive emergency in the pre-implementation cohort, 34 (35%) received treatment with a rapid acting antihypertensive medication within one hour compared with 54 of 104 (55%) of patients in the post-implementation cohort (35% vs 55%, RR 1.40 95% CI 1.07-1.82). Significantly more patients followed up for a blood pressure check within one week of discharge (41% vs 31%; p = 0.02). There was not a significant effect on the administration of IV magnesium sulfate or initiation of oral medications postpartum.
An automated EHR alert improved timely administration of rapid-acting antihypertensive medications for hypertensive emergency and has the potential to improve compliance with national preeclampsia guidelines.
在学术型分娩地,利用自动化电子病历(EHR)警报,改善对妊娠高血压急症的速效降压药物的合理及时应用,以管理妊娠高血压急症。
在现有的 EHR 中嵌入了一个自动警报,通知提供者有记录的严重血压范围,定义为收缩压(SBP)≥160mmHg 或舒张压(DBP)≥110mmHg。回顾性图表审查用于评估在实施警报之前和之后(称为实施前和实施后队列)的适当干预措施。
主要结果是为管理高血压急症而合理应用速效降压药物。次要结果包括:适当应用静脉(IV)硫酸镁预防抽搐、产后开始口服降压药物,以及在出院后血压评估的适当随访时间。
在实施前队列中,98 例被确定为高血压急症的患者中,有 34 例(35%)在 1 小时内接受了速效降压药物治疗,而在实施后队列的 104 例患者中,有 54 例(55%)接受了治疗(35%对 55%,RR 1.40,95%CI 1.07-1.82)。出院后一周内,有更多的患者进行了血压检查(41%对 31%;p=0.02)。IV 硫酸镁的应用或产后口服药物的开始没有显著影响。
自动化 EHR 警报改善了高血压急症的速效降压药物的合理及时应用,并有潜力提高对全国子痫前期指南的遵守程度。