Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia
Ngangk Yira Research Centre for Aboriginal Health and Social Equity, Murdoch University, Murdoch, Western Australia, Australia.
J Epidemiol Community Health. 2021 Dec;75(12):1187-1194. doi: 10.1136/jech-2020-214507. Epub 2021 May 18.
The health disadvantages faced by Australian Aboriginal peoples are evidenced in early life, although few studies have focused on the reasons for population-level inequalities in more severe adverse outcomes. This study aimed to examine the scale of disparity in severe neonatal morbidity (SNM) and mortality between Aboriginal and non-Aboriginal births and quantify the relative contributions of important maternal and infant factors.
A retrospective cohort study with singleton live births (≥32 weeks' gestation) was conducted using Western Australia linked whole population datasets, from 1999 to 2015. Aboriginal status was determined based on the mothers' self-reported ethnic origin. An Australian validated indicator was adapted to identify neonates with SNM. The Oaxaca-Blinder method was employed to calculate the contribution of each maternal and infant factor to the disparity in SNM and mortality.
Analyses included 425 070 births, with 15 967 (3.8%) SNM and mortality cases. The disparity in SNM and mortality between Aboriginal and non-Aboriginal births was 2.9 percentage points (95% CI 2.6 to 3.2). About 71% of this gap was explained by differences in modelled factors including maternal area of residence (23.8%), gestational age (22.2%), maternal age (7.5%) and antenatal smoking (7.2%).
There is a considerable disparity in SNM and mortality between Aboriginal and non-Aboriginal births in Western Australia with the majority of this related to differences in maternal sociodemographic factors, antenatal smoking and gestational age. Public health programmes targeting these factors may contribute to a reduction in early life health differentials and benefit Aboriginal population health through the life course.
澳大利亚原住民在生命早期就面临健康劣势,尽管很少有研究关注导致人群中更严重不良结局不平等的原因。本研究旨在探讨澳大利亚原住民和非原住民出生的严重新生儿发病率(SNM)和死亡率的差异程度,并量化重要的母婴因素的相对贡献。
使用西澳大利亚州的全人群关联数据集,进行了一项回顾性队列研究,纳入了 1999 年至 2015 年间的单胎活产(≥32 周妊娠)。根据母亲的自我报告的种族来源确定原住民身份。采用澳大利亚验证的指标来识别有 SNM 的新生儿。采用 Oaxaca-Blinder 方法计算每个母婴因素对 SNM 和死亡率差异的贡献。
分析包括 425070 例分娩,其中有 15967 例(3.8%)出现 SNM 和死亡。原住民和非原住民出生的 SNM 和死亡率差异为 2.9 个百分点(95%CI 2.6 至 3.2)。约 71%的差距可以用模型因素的差异来解释,包括母亲居住地(23.8%)、胎龄(22.2%)、母亲年龄(7.5%)和产前吸烟(7.2%)。
在西澳大利亚州,原住民和非原住民出生的 SNM 和死亡率存在显著差异,其中大部分与母婴社会人口因素、产前吸烟和胎龄的差异有关。针对这些因素的公共卫生计划可能有助于减少生命早期的健康差异,并通过整个生命周期改善原住民的人口健康。