原发性脊髓内淋巴瘤（PISCL）：一种罕见且诊断具有挑战性的疾病。
Primary intramedullary spinal-cord lymphoma (PISCL): a rare entity with a challenging diagnosis.
机构信息
Neurology, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Coimbra, Portugal
Neurology, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Coimbra, Portugal.
出版信息
BMJ Case Rep. 2021 May 19;14(5):e242548. doi: 10.1136/bcr-2021-242548.
Primary intramedullary spinal-cord lymphoma (PISCL) is a rare cause of myelopathy and constitutes only 1% of central nervous system lymphomas. Delay to diagnosis is common due to its rarity, its similarity to other causes of myelopathy and the difficulties in obtaining pathological diagnosis. We report a case of PISCL and discuss the challenges faced on diagnosis, namely the impact of corticosteroids on histological findings, the usefulness of MRI, positron-emission tomography/CT (PET/CT) and repeated lumbar punctures.
原发性脊髓内淋巴瘤（PISCL）是一种罕见的脊髓病病因，仅占中枢神经系统淋巴瘤的 1%。由于其罕见性、与其他脊髓病病因的相似性以及获取病理诊断的困难，诊断常被延误。我们报告了一例 PISCL 病例，并讨论了诊断所面临的挑战，即皮质类固醇对组织学发现的影响、MRI、正电子发射断层扫描/计算机断层扫描（PET/CT）和重复腰椎穿刺的作用。
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