Maryland Spine Center, Baltimore, MD.
Clin Spine Surg. 2021 Aug 1;34(7):E397-E402. doi: 10.1097/BSD.0000000000001202.
This was a prospective cohort study (observational-retrospective chart review).
The objective of this study was to determine clinical rates and correlations of postoperative urinary retention (POUR) in elective spine decompression and fusion procedures.
POUR is a common postoperative complication that often has a major adverse impact on a patient's recovery from elective lumbar spine surgery. The etiology of POUR in most cases is unknown. Patients undergoing lumbar spine surgery are considered to be at increased risk for POUR due to prone positioning during surgery and intraoperative cauda equina nerve root manipulation. Current studies reporting on POUR after elective spine surgery provide limited insight regarding risk factors and effective prevention strategies for this at-risk population. The purpose of this study is to identify risk factors for POUR after elective lumbar spine surgery and strategies for reducing its incidence.
Two hundred consecutive patients aged 50 years or older undergoing combined lumbar decompression and fusion procedures over a 5-month period at a single institution were prospectively observed. Demographic and clinical data were prospectively recorded, including: medical history, surgical data, medications administered, complications, and postoperative hospital course. Factors correlating with POUR through a univariate analysis with P≤0.20 were considered for multivariate analysis.
POUR occurred in 19 of 200 patients. Those with POUR were more likely to be male (20% vs. 4%, odds ratio=6.2). Administration of scopolamine (P=0.02), neostigmine (P=0.01), and the total number of levels operated on (P=0.02) were found to be independent risk factors for the development of POUR. Length of surgery, surgical level, the performance of an interbody fusion did not have a bearing on the development of POUR (P>0.05).
We describe a single institution's experience of POUR incidence in 200 consecutive patients aged 50 years or older undergoing single or multilevel lumbar spine fusion procedures by 1 of 4 surgeons. Specific demographic and clinical risk factors were identified and a codified classification for POUR in a surgical population is presented.The results of this study will help clinicians appropriately counsel patients undergoing elective lumbar fusion about the potential development of POUR. The perioperative administration of scopolamine and neostigmine should be cautiously considered in men over 50 years of age due to the increased POUR risk.
Perioperative scopolamine and neostigmine administration in men over 50 should be avoided when possible to minimize the risk of POUR.
Level III.
这是一项前瞻性队列研究(观察性回顾性图表审查)。
本研究的目的是确定择期脊柱减压融合手术中术后尿潴留(POUR)的临床发生率和相关性。
POUR 是一种常见的术后并发症,通常会对腰椎手术患者的康复产生重大不利影响。在大多数情况下,POUR 的病因尚不清楚。由于手术中俯卧位和术中马尾神经根操作,接受腰椎手术的患者被认为有发生 POUR 的高风险。目前,关于择期脊柱手术后 POUR 的研究报告,对于该高危人群的危险因素和有效预防策略提供的见解有限。本研究的目的是确定择期腰椎手术后 POUR 的危险因素,并制定降低其发生率的策略。
在一家机构中,连续观察了 5 个月内 200 例年龄在 50 岁或以上接受联合腰椎减压融合手术的患者。前瞻性记录了人口统计学和临床数据,包括:病史、手术数据、用药、并发症和术后住院过程。通过 P≤0.20 的单变量分析与 POUR 相关的因素被认为需要进行多变量分析。
200 例患者中,19 例发生 POUR。发生 POUR 的患者更可能为男性(20% vs. 4%,优势比=6.2)。给予东莨菪碱(P=0.02)、新斯的明(P=0.01)和手术操作的总节段数(P=0.02)被发现是 POUR 发展的独立危险因素。手术时间、手术节段、是否进行椎间融合术与 POUR 的发生无相关性(P>0.05)。
我们描述了 200 例年龄在 50 岁或以上的连续患者,由 4 名外科医生中的 1 名进行单节段或多节段腰椎融合手术的单机构经验。确定了特定的人口统计学和临床危险因素,并提出了手术人群中 POUR 的分类方法。本研究的结果将帮助临床医生就潜在的 POUR 发展,适当地向接受择期腰椎融合术的患者提供咨询。由于 POUR 风险增加,50 岁以上男性应谨慎考虑围手术期给予东莨菪碱和新斯的明。
在可能的情况下,应避免 50 岁以上男性围手术期给予东莨菪碱和新斯的明,以最大限度地降低 POUR 的风险。
III 级。