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卡普格拉综合征和虚构症伴抗 NMDAR 脑炎的经典甲状腺乳头状癌:首例报告。

Capgras syndrome and confabulation unfurling anti NMDAR encephalitis with classical papillary thyroid carcinoma: First reported case.

机构信息

Dept of Neurology, Bangur Institute of Neurosciences, 52/1A SN Pandit Street, Kolkata, West Bengal, India.

Dept of Neurology, Bangur Institute of Neurosciences, 52/1A SN Pandit Street, Kolkata, West Bengal, India.

出版信息

J Neuroimmunol. 2021 Aug 15;357:577611. doi: 10.1016/j.jneuroim.2021.577611. Epub 2021 May 19.

Abstract

Anti NMDA Receptor encephalitis (ANMDARE) is an immune mediated disease of the central nervous system, caused by circulating antibodies against the NMDA receptor present on neuronal surface. It is known to cause a spectrum of disease ranging from mild behavioral and psychiatric manifestations to full blown seizures, dyskinesias and altered sensorium. It can also be paraneoplastic presentation of a hidden tumor, most commonly ovarian teratoma. Here we present a case of ANMDARE with intriguing presentation of Capgras syndrome and confabulations, who was found to have a malignant papillary thyroid carcinoma, which has been rarely reported.

摘要

抗 N-甲基-D-天冬氨酸受体脑炎 (ANMDARE) 是一种由神经元表面 NMDA 受体的循环抗体引起的中枢神经系统自身免疫性疾病。它已知会引起一系列疾病,从轻微的行为和精神表现到全面发作、运动障碍和感觉改变。它也可能是隐匿性肿瘤的副肿瘤表现,最常见的是卵巢畸胎瘤。在这里,我们介绍了一例具有奇特的卡普格拉综合征和虚构症表现的 ANMDARE 病例,该患者被发现患有恶性甲状腺乳头状癌,这种情况很少见。

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