Research Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Cornea, Anterior Segment and Refractive Surgery Department, University of Ottawa Eye Institute, Ottawa, Ontario, Canada.
Eur J Ophthalmol. 2021 Nov;31(6):3500-3504. doi: 10.1177/11206721211020648. Epub 2021 May 31.
To assess the vision-related quality of life (VQoL) for patients with advanced keratoconus (KC) after primary keratoplasty.
This was a cross-sectional study, undertaken at the King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia, in December 2015. Adults (aged 22-75 years) were interviewed via telephone with regard to their VQoL, on the average, 5 years after undergoing primary keratoplasty for advanced KC. VQoL was measured using the Visual Functioning Index (VF-14, Arabic version). The relationship between VQoL and different demographic and clinical factors was evaluated using linear regression.
Ninety-five adults participated in the study (54.7 % males; mean age at the interview = 32.05 ± 7.18 years). Eighty-seven (91.6%) of them had undergone PKP. The overall mean VF-14 score was 86.19% (SD: 12.91). VF-14 score was significantly lower for individuals with higher log average K (beta coefficient, -28.32; 95% confidence interval [CI], -55.59 to -1.04; = 0.042) and hazy graft (beta coefficient, -12.76; 95% CI, -21.16 to -4.36; = 0.003) adjusting for the effect of keratoplasty technique and BCVA in the better eye at the last follow up.
This study suggests that most patients with advanced keratoconus had satisfactory VQoL after primary keratoplasty. Certain subgroups may benefit less substantially than others and would need a particular attention.
评估原发性角膜移植术后晚期圆锥角膜患者的视觉相关生活质量(VQoL)。
这是一项横断面研究,于 2015 年 12 月在沙特阿拉伯利雅得的 King Khaled 眼科专科医院进行。通过电话对成年人(年龄 22-75 岁)进行访谈,了解他们在接受原发性角膜移植治疗晚期圆锥角膜后平均 5 年的 VQoL。使用视觉功能指数(VF-14,阿拉伯语版)测量 VQoL。使用线性回归评估 VQoL 与不同人口统计学和临床因素之间的关系。
95 名成年人参与了这项研究(54.7%为男性;访谈时的平均年龄为 32.05±7.18 岁)。其中 87 人(91.6%)接受了穿透性角膜移植术。总体平均 VF-14 得分为 86.19%(SD:12.91)。VF-14 评分在以下人群中明显较低:具有较高的平均 log K(β系数,-28.32;95%置信区间[CI],-55.59 至-1.04; = 0.042)和混浊移植物的个体(β系数,-12.76;95% CI,-21.16 至-4.36; = 0.003),调整了在最后一次随访时较好眼中的角膜移植技术和 BCVA 的影响。
这项研究表明,大多数晚期圆锥角膜患者在接受原发性角膜移植术后具有满意的 VQoL。某些亚组可能受益较小,需要特别关注。