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COVID-19 住院幸存者中年龄超过 70 岁者的健康状况:3 个月时的观察性随访研究。

Health status in survivors older than 70 years after hospitalization with COVID-19: observational follow-up study at 3 months.

机构信息

Department of Geriatric, Hospital Central de la Cruz Roja, San José y Santa Adela, Avenida Reina Victoria 26, 28003, Madrid, Spain.

Cardiology Department, Hospital Central de la Cruz Roja, San José y Santa Adela, Madrid, Spain.

出版信息

Eur Geriatr Med. 2021 Oct;12(5):1091-1094. doi: 10.1007/s41999-021-00516-1. Epub 2021 May 31.

Abstract

PURPOSE

To analyze factors associated with mortality at 3 months and readmissions, functional and cognitive decline, anorexia and affective disorders in patients aged > 70 years surviving after hospital admission for SARS-CoV-2.

METHODS

Patients aged > 70 years, discharged after hospitalization with COVID-19.

OUTCOME VARIABLES

mortality, readmissions, functional and cognitive impairment, anorexia and mood disorder.

RESULTS

165 cases at 3 months after hospital discharge, 8.5% died and 20% required at least one hospital readmission. The presence of severe dependence at discharge (BI < 40) was associated at 3 months with a higher risk of mortality (OR 5.08; 95% CI 1.53-16.91) and readmissions (OR 4.53; 95% CI 1.96-10.49). The post-hospitalization functional deterioration was associated with persistence of deterioration at 3 months (OR 24.57; 95% CI 9.24-65.39), cognitive deterioration (OR 2.32; 95% CI 1.03-5.25) and affective (OR 4.40; 95% CI 1.84-10.55) CONCLUSIONS: Loss function in older people after hospitalization by COVID-19 may contribute to identify patients with a higher risk of sequelae in the short term that require closer follow-up.

摘要

目的

分析与 COVID-19 后住院存活的年龄>70 岁患者 3 个月时死亡率、再入院率、功能和认知障碍、厌食和情感障碍相关的因素。

方法

年龄>70 岁,COVID-19 住院后出院的患者。

结局变量

死亡率、再入院率、功能和认知障碍、厌食和情绪障碍。

结果

出院后 3 个月时,165 例患者中有 8.5%死亡,20%至少需要再次住院。出院时严重依赖(BI<40)与 3 个月时死亡率(OR 5.08;95%CI 1.53-16.91)和再入院率(OR 4.53;95%CI 1.96-10.49)较高相关。住院后功能恶化与 3 个月时恶化持续存在(OR 24.57;95%CI 9.24-65.39)、认知恶化(OR 2.32;95%CI 1.03-5.25)和情感(OR 4.40;95%CI 1.84-10.55)相关。

结论

COVID-19 后住院老年人功能丧失可能有助于识别短期内有更高后遗症风险的患者,需要更密切的随访。

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