Department of Pathology and Laboratory Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Clin Microbiol Rev. 2021 Jun 16;34(3):e0007019. doi: 10.1128/CMR.00070-19. Epub 2021 Jun 2.
The variety and complexity of ocular infections have increased significantly in the last decade since the publication of , (L. D. Gray, P. H. Gilligan, and W. C. Fowler, , , 2010). The purpose of this practical guidance document is to review, for individuals working in clinical microbiology laboratories, current tools used in the laboratory diagnosis of ocular infections. This document begins by describing the complex, delicate anatomy of the eye, which often leads to limitations in specimen quantity, requiring a close working bond between laboratorians and ophthalmologists to ensure high-quality diagnostic care. Descriptions are provided of common ocular infections in developed nations and neglected ocular infections seen in developing nations. Subsequently, preanalytic, analytic, and postanalytic aspects of laboratory diagnosis and antimicrobial susceptibility testing are explored in depth.
自 2010 年出版以来,眼科感染的种类和复杂性显著增加。本实用指导文件的目的是为临床微生物学实验室工作的个人回顾目前在眼科感染的实验室诊断中使用的工具。本文首先描述了眼睛复杂、脆弱的解剖结构,这往往导致标本数量有限,需要检验人员和眼科医生密切合作,以确保高质量的诊断护理。本文还描述了发达国家常见的眼部感染和发展中国家常见的被忽视的眼部感染。随后,深入探讨了实验室诊断和抗菌药物敏感性测试的分析前、分析中和分析后方面。