Kaplan A, Israel F
Department of Pediatrics, University of North Carolina, Chapel Hill 27514.
Am J Med Sci. 1988 Jul;296(1):57-8. doi: 10.1097/00000441-198807000-00010.
Patients with chronic granulomatous disease are uniquely susceptible to infection with catalase-producing bacteria. Staphylococcus aureus, Klebsiella, Escherichia coli and Serratia marcescans are common infecting organisms. A 17-month-old boy with Corynebacterium aquaticum bacteremia is reported. This is only the third documented infection with this non-JK diphtheroid and the first case infection in a patient with chronic granulomatous disease. It is likely that our patient's underlying immune defect predisposed him to infection with this unusual, catalase-producing organism. Although these bacteria are common contaminants and rarely infecting agents, true infection should be considered in patients with chronic granulomatous disease from whom a diphtheroid is isolated.
慢性肉芽肿病患者对产过氧化氢酶细菌感染具有独特的易感性。金黄色葡萄球菌、克雷伯菌、大肠杆菌和粘质沙雷菌是常见的感染病原体。本文报道了一名17个月大患水生棒状杆菌菌血症的男孩。这是该非JK类白喉杆菌有记录的第三例感染，也是慢性肉芽肿病患者中的首例感染病例。很可能该患者潜在的免疫缺陷使其易感染这种不常见的产过氧化氢酶微生物。尽管这些细菌是常见的污染物，很少作为感染病原体，但对于从其体内分离出类白喉杆菌的慢性肉芽肿病患者，应考虑存在真正感染。
