Pediatric Pulmonary Institute, Ruth Children's Hospital, Rambam Health Care Campus, Haifa, Israel.
Faculty of Medicine, Technion, Haifa, Israel.
Pediatr Pulmonol. 2021 Aug;56(8):2736-2739. doi: 10.1002/ppul.25511. Epub 2021 Jun 2.
A 16-year-old adolescent presented with dry cough, fever, weight loss, night sweats, exercise intolerance, and eosinophilia. Computed tomography showed consolidations with "reverse butterfly" pattern. He responded well to corticosteroids but had frequent relapses. He became steroid dependent and developed steroid related morbidity. Benralizumab was prescribed with complete resolution of eosinophilia and lung infiltrates with no adverse effect.
一名 16 岁青少年出现干咳、发热、体重减轻、盗汗、运动不耐受和嗜酸性粒细胞增多。计算机断层扫描显示有“蝶翼样”改变的实变影。他对皮质类固醇反应良好,但频繁复发。他成为皮质类固醇依赖者,并出现皮质类固醇相关的发病率。使用贝那鲁单抗后,嗜酸性粒细胞增多和肺部浸润完全消退,无不良反应。