Department of Orthopedic Surgery, New York University Langone Health, New York, NY, USA.
Department of Radiology, New York University Langone Health, New York, NY, USA.
Cartilage. 2021 Dec;13(1_suppl):886S-893S. doi: 10.1177/19476035211021911. Epub 2021 Jun 2.
The purpose of the current study is to evaluate the clinical and radiographic outcomes at early to midterm follow-up between fresh precut cores versus hemi-condylar osteochondral allograft (OCAs) in the treatment of symptomatic osteochondral lesions.
A retrospective review of patients who underwent an OCA was performed. Patient matching between those with OCA harvested from an allograft condyle/patella or a fresh precut allograft core was performed to generate 2 comparable groups. The cartilage at the graft site was assessed with use of a modified Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) scoring system and patient-reported outcomes were collected.
Overall, 52 total patients who underwent OCA with either fresh precut OCA cores ( = 26) and hemi-condylar OCA ( = 26) were pair matched at a mean follow-up of 34.0 months (range 12 months to 99 months). The mean ages were 31.5 ± 10.7 for fresh precut cores and 30.9 ± 9.8 for hemi-condylar ( = 0.673). Males accounted for 36.4% of the overall cohort, and the mean lesion size for fresh precut OCA core was 19.6 mm compared to 21.2 mm for whole condyle ( = 0.178). There was no significant difference in patient-reported outcomes including Visual Analogue Scale, Knee Injury and Osteoarthritis Outcome Score for Joint Replacement, and Tegner ( > 0.5 for each), or in MOCART score (69.2 vs. 68.3, = 0.93).
This study found that there was no difference in patient-reported clinical outcomes or MOCART scores following OCA implantation using fresh precut OCA cores or size matched condylar grafts at early to midterm follow-up.
本研究旨在评估新鲜预切开骨芯与半髁骨软骨同种异体移植物(OCA)治疗症状性骨软骨病变的早期至中期随访时的临床和影像学结果。
对接受 OCA 治疗的患者进行回顾性研究。对来自同种异体髁/髌骨或新鲜预切开同种异体骨芯的 OCA 患者进行匹配,以生成 2 个可比组。使用改良的磁共振观察软骨修复组织(MOCART)评分系统评估移植物部位的软骨,并收集患者报告的结果。
总体而言,52 例患者接受 OCA 治疗,其中 26 例采用新鲜预切开 OCA 骨芯,26 例采用半髁 OCA,平均随访 34.0 个月(12 个月至 99 个月)。新鲜预切开骨芯组的平均年龄为 31.5 ± 10.7 岁,半髁组为 30.9 ± 9.8 岁(=0.673)。男性占总队列的 36.4%,新鲜预切开 OCA 骨芯的平均病变大小为 19.6mm,而整个髁的病变大小为 21.2mm(=0.178)。在患者报告的结果方面,包括视觉模拟评分、膝关节损伤和骨关节炎结果评分关节置换和 Tegner(每项 >0.5),或在 MOCART 评分(69.2 对 68.3,=0.93)方面,两组之间无显著差异。
本研究发现,在早期至中期随访时,使用新鲜预切开 OCA 骨芯或大小匹配的髁状突移植物进行 OCA 植入后,患者报告的临床结果或 MOCART 评分无差异。