Samushiya M A, Kryzhanovsky S M, Ragimova A A, Berishvili T Z, Chorbinskaya S A, Ivannikova E I
Central State Medical Academy of Department of Presidential Affairs, Moscow, Russia.
National Research University «Higher School of Economics», Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(4. Vyp. 2):49-54. doi: 10.17116/jnevro202112104249.
To study the prevalence of anxiety-depressive disorders and sleep disorders in their structure among patients hospitalized in connection with COVID-19, as well as to develop differentiated recommendations for their therapy in patients with new coronavirus infection.
In this publication, the authors present preliminary results of their own observations of psychoemotional disorders and sleep disorders in their structure in patients with a new coronavirus infection. We analyzed the data of 119 patients (aged 47 to 69 years, male and female), conducted a detailed interview, including using telemedicine technologies, and assessed the scales: The hospital Anxiety and Depression Scale (HADS), subjective the asthenia rating scale (MFI-20, Multidimensional Fatigue Inventory) and the Pittsburgh Sleep Quality Index (PSQI) questionnaire.
According to the results of the HADS questionnaire, clinically pronounced anxiety-depressive symptoms were observed in 33 (28%) patients of 119 hospitalized in connection with the diagnosis of COVID-19. Of them, only clinically significant anxiety was recorded in 11% of cases (=13), in 5 (4%) patients - clinically significant depression, an increase in both subscales of anxiety and depression - in 13% (=15). An increase in the MFI-20 scale (more than 20 points) was found in 87 (73%) patients, sleep disorders in accordance with the PSQI questionnaire was recorded in 32 (27%) patients.
According to the results of the study, it was noted that in most patients with COVID-19, along with a depressive symptom complex, anxiety and hypochondriacal disorders, an asthenic symptom complex, sleep disturbances with difficulty falling asleep, and dissatisfaction with the quality of sleep are recorded. Differentiated recommendations for the treatment of the studied conditions have been developed, taking into account the side effects of the prescribed drugs, drug interactions and the characteristics of the somatic status of patients. The choice of the drug should be based on the severity of the violations identified.
研究因新型冠状病毒肺炎(COVID-19)住院患者中焦虑抑郁障碍和睡眠障碍的患病率及其构成,并针对新型冠状病毒感染患者制定差异化的治疗建议。
在本出版物中,作者展示了对新型冠状病毒感染患者心理情绪障碍和睡眠障碍构成的自身观察的初步结果。我们分析了119例患者(年龄47至69岁,男女均有)的数据,进行了详细访谈,包括使用远程医疗技术,并评估了以下量表:医院焦虑抑郁量表(HADS)、主观虚弱评定量表(MFI-20,多维疲劳量表)和匹兹堡睡眠质量指数(PSQI)问卷。
根据HADS问卷结果,在119例因COVID-19诊断住院的患者中,有33例(28%)出现了临床明显的焦虑抑郁症状。其中,仅11%(=13例)记录到临床显著焦虑,5例(4%)患者有临床显著抑郁,焦虑和抑郁两个子量表均升高的情况占13%(=15例)。87例(73%)患者的MFI-20量表升高(超过20分),32例(27%)患者根据PSQI问卷记录有睡眠障碍。
根据研究结果,注意到在大多数COVID-19患者中,除了抑郁症状群外,还记录到焦虑和疑病障碍、虚弱症状群、入睡困难的睡眠障碍以及对睡眠质量的不满意。考虑到所开药物的副作用、药物相互作用以及患者躯体状况的特点,已制定了针对所研究病症的差异化治疗建议。药物的选择应基于所确定的违规严重程度。